Trial Outcomes & Findings for Reminder-cue Scanning Training for Homonymous Visual Field Loss (NCT NCT06136169)

NCT ID: NCT06136169

Last Updated: 2026-05-12

Results Overview

Percentage of intersections at which an early large head scan was made to the side of the field loss

Recruitment status

ACTIVE_NOT_RECRUITING

Study phase

NA

Target enrollment

16 participants

Primary outcome timeframe

Pre-training, post-training (1 week)

Results posted on

2026-05-12

Participant Flow

Participants were recruited from local ophthalmology outpatient clinics

Participant milestones

Participant milestones
Measure
Intervention
All participants were allocated to receive three sessions of reminder-cue scanning training in the driving simulator
Intervention
STARTED
16
Intervention
COMPLETED
16
Intervention
NOT COMPLETED
0
Follow up
STARTED
16
Follow up
COMPLETED
16
Follow up
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Reminder-cue Scanning Training for Homonymous Visual Field Loss

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intervention
n=16 Participants
All participants were allocated to receive three sessions of reminder-cue scanning training in the driving simulator
Age, Continuous
52.5 years
n=1512 Participants
Sex: Female, Male
Female
7 Participants
n=1512 Participants
Sex: Female, Male
Male
9 Participants
n=1512 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=1512 Participants
Race (NIH/OMB)
Asian
1 Participants
n=1512 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=1512 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=1512 Participants
Race (NIH/OMB)
White
15 Participants
n=1512 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=1512 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=1512 Participants

PRIMARY outcome

Timeframe: Pre-training, post-training (1 week)

Percentage of intersections at which an early large head scan was made to the side of the field loss

Outcome measures

Outcome measures
Measure
Intervention
n=52 Intersections
All participants were allocated to receive three sessions of reminder-cue scanning training in the driving simulator
Rate of Early Large Head Scans to the Side of the Field Loss
Pre-training
18 Percentage of intersections
Interval 9.0 to 26.0
Rate of Early Large Head Scans to the Side of the Field Loss
1-week post-training
84 Percentage of intersections
Interval 77.0 to 91.0

PRIMARY outcome

Timeframe: Pre-training, Post-training (1 week)

Percentage of hazards detected out of the total number of hazards on the side of the field loss

Outcome measures

Outcome measures
Measure
Intervention
n=10 Hazards
All participants were allocated to receive three sessions of reminder-cue scanning training in the driving simulator
Detection Rate for Hazards on the Side of the Field Loss
Pre-training
56 Percentage of hazards
Interval 41.0 to 70.0
Detection Rate for Hazards on the Side of the Field Loss
1-week post-training
86 Percentage of hazards
Interval 76.0 to 95.0

SECONDARY outcome

Timeframe: Pre-training, Post-training (1 week)

Number of head scans per intersection to the side of the field loss. A validated algorithm was used to detect head scans, defined as lateral rotations of the head away from the straight ahead position toward either the left or the right, which exceeded a predefined threshold based on the participant's distance to the intersection: ≥ 4° (100 to 50 m to intersection), ≥ 6° (50 to 20m), ≥ 10° (20 to 0m). Savage SW, Zhang L, Swan G, Bowers AR (2020) The effects of age on the contributions of head and eye movements to scanning behavior at intersections. Transp Res Part F Traffic Psychol Behav. 73:128-142. Swan G, Goldstein RB, Savage SW, Zhang L, Ahmadi A, Bowers AR (2021) Automatic processing of gaze movements to quantify gaze scanning behaviors in a driving simulator. Behav Res Methods. 53(2): 487-506

Outcome measures

Outcome measures
Measure
Intervention
n=52 Intersections
All participants were allocated to receive three sessions of reminder-cue scanning training in the driving simulator
Number of Head Scans to the Side of the Field Loss
Pre-training
2.2 Number of head scans per intersection
Interval 1.8 to 2.7
Number of Head Scans to the Side of the Field Loss
1-week post-training
3.5 Number of head scans per intersection
Interval 3.1 to 4.0

SECONDARY outcome

Timeframe: Pre-training, Post-training (1 week)

Mean magnitude (in degrees) of head scans to the side of the field loss. A validated algorithm was used to detect head scans, defined as lateral rotations of the head away from the straight ahead position toward either the left or the right, which exceeded a predefined threshold based on the participant's distance to the intersection: ≥ 4° (100 to 50 m to intersection), ≥ 6° (50 to 20m), ≥ 10° (20 to 0m). The magnitude is the lateral angular extent of the scan measured from the straight-ahead position to the furthest lateral position to the left or right. Savage SW, Zhang L, Swan G, Bowers AR (2020) The effects of age on the contributions of head and eye movements to scanning behavior at intersections. Transp Res Part F Traffic Psychol Behav. 73:128-142. Swan G, Goldstein RB, Savage SW, Zhang L, Ahmadi A, Bowers AR (2021) Automatic processing of gaze movements to quantify gaze scanning behaviors in a driving simulator. Behav Res Methods. 53(2): 487-506

Outcome measures

Outcome measures
Measure
Intervention
n=52 Intersections
All participants were allocated to receive three sessions of reminder-cue scanning training in the driving simulator
Magnitude of Head Scans to the Side of the Field Loss
Pre-training
23.9 Degrees
Interval 20.3 to 27.5
Magnitude of Head Scans to the Side of the Field Loss
1-week post-training
27.5 Degrees
Interval 23.8 to 31.2

SECONDARY outcome

Timeframe: Pre-training, Post-training (1 week)

Mean time (in seconds) between the hazard appearing and the horn-press response

Outcome measures

Outcome measures
Measure
Intervention
n=10 Hazards
All participants were allocated to receive three sessions of reminder-cue scanning training in the driving simulator
Response Times to Hazards on the Side of the Field Loss
Pre-training
2.7 Seconds
Interval 2.4 to 3.0
Response Times to Hazards on the Side of the Field Loss
1-week post-training
1.9 Seconds
Interval 1.6 to 2.1

Adverse Events

Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Alex Bowers

Schepens Eye Research Institute of Mass Eye and Ear

Phone: 617 912 2512

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place