Effect of IMO on Intestinal Microbiota Translocation in Cirrhosis
NCT06134544 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18
Last updated 2024-04-12
Summary
The goal of this intervention clinical trial is to learn about the protection of isomaltooligosaccharides (IMO) on intestinal bacterial translocation in patients with liver cirrhosis. The main question is to answer the changes of LPS after adminstration of IMO.
Conditions
- Decompensated Cirrhosis
Interventions
- DIETARY_SUPPLEMENT
-
Isomaltooligosaccharides (IMO)
Patients will still receive standard treatment, including medicine and other invasive treatment.
Sponsors & Collaborators
-
Nanfang Hospital, Southern Medical University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-11-25
- Primary Completion
- 2024-06-01
- Completion
- 2024-07-01
Countries
- China
Study Locations
More Related Trials
-
A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis
NCT06461208 ·Status: RECRUITING ·Phase: PHASE3
-
Treatment of Nonalcoholic Fatty Liver Disease With Probiotics and Prebiotics
NCT00870012 ·Status: COMPLETED ·Phase: NA
-
Trial of Faecal Microbiota Transplantation in Cirrhosis
NCT02862249 ·Status: COMPLETED ·Phase: PHASE3
-
Probiotic Supplement Versus Placebo for the Treatment of Patients With Non-alcoholic Fatty Liver Disease
NCT06491342 ·Status: COMPLETED ·Phase: NA
-
Intestinal Microbiota Transplantation for Nonalcoholic Fatty Liver Disease
NCT03648086 ·Status: UNKNOWN ·Phase: NA
-
Faecal Microbiota Transplantation for Liver Cirrhosis
NCT04932577 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Adults NAFLD Patients (DELI_NAFLD Study)
NCT05804422 ·Status: COMPLETED ·Phase: NA
-
Fecal Microbiota Transplantation for Liver Failure
NCT05170971 ·Status: RECRUITING ·Phase: NA
-
Alterations of Gut Microbiota and Serum Biochemical Markers in DILI Patients
NCT05465642 ·Status: UNKNOWN
-
Effect of Metformin on Disease Progression in Patients With Cryptogenic Cirrhosis (NASH-related Cirrhosis) With Diabetes or Impaired Glucose Tolerance or Insulin Resistance
NCT02234440 ·Status: COMPLETED ·Phase: NA
-
Safety Evaluation of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis
NCT05006430 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Implications of Fecal Microbiota Transplantation in Modulating the Effects of Liver Cirrhosis
NCT06478602 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Effectiveness of Sulfasalazine in the Treatment of Liver Fibrosis/Cirrhosis.
NCT06293378 ·Status: RECRUITING ·Phase: NA
-
Efficacy and Safety of Fecal Microbiota Transplant for Secondary Prophylaxis of Hepatic Encephalopathy
NCT05229289 ·Status: UNKNOWN ·Phase: NA
-
Effects of Fecal Microbiota Transplantation on Weight in Obese Patients With Non-alcoholic Fatty Liver Disease
NCT04594954 ·Status: UNKNOWN ·Phase: NA
-
A Comparison of Fecal Microbiota Transplantation and Steroid Therapy in Patients With Severe Alcoholic Hepatitis.
NCT03091010 ·Status: UNKNOWN ·Phase: NA
-
The Efficacy and Safety of Chiglitazar in Patients with MAFLD-related Cirrhosis
NCT06773221 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Prospective, Randomized, Placebo-Controlled Pilot Study to Characterize the Intestinal Microbiome and to Evaluate the Safety and Fecal Microbiome Changes Following Administration of Lyophilized PRIM-DJ2727 or Placebo Given Orally in Subjects With Nonalcoholic Fatty Liver Disease
NCT04371653 ·Status: WITHDRAWN ·Phase: PHASE2
-
The Effect of Calcium β-hydroxy-β-methylbutyrate (CaHMB) Supplementation in Sarcopenia in Liver Cirrhosis
NCT03605147 ·Status: UNKNOWN ·Phase: NA
-
Microbiome-Mediated Gut Dysfunction in Non-Alcoholic Fatty Liver Disease
NCT05209100 ·Status: COMPLETED
-
A Trial to Study the Influence of Growth Factors on Bone Marrow and Hepatic Regeneration in Patients With Decompensated Cirrhosis.
NCT01902511 ·Status: COMPLETED ·Phase: NA
-
Investigation of Synbiotic Treatment in NAFLD
NCT01680640 ·Status: COMPLETED ·Phase: NA
-
Clinical Trial of Umbilical Cord Mesenchymal Stem Cell Transfusion in Decompensated Liver Cirrhosis
NCT03529136 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Oryz-Aspergillus Enzyme and Pancreatin Tablet in Patients With Cirrhosis and Malnutrition
NCT04057326 ·Status: UNKNOWN ·Phase: NA
-
Effect of Probiotic and Smectite Gel on NAFLD
NCT03614039 ·Status: COMPLETED ·Phase: NA