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Developing a Nationwide Registry to Track Longitudinal Clinical Outcomes of Corneal Surgery and Disease

NCT06101017 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 19

Last updated 2026-02-19

No results posted yet for this study

Summary

The goal is to develop a nationwide registry to track longitudinal clinical outcomes of and store imaging data related to numerous corneal conditions. There are two main objectives including the establishment of the first nationwide corneal transplant registry in the United States to include information related to the donor tissue, recipient, surgical procedure, and long-term clinical outcomes. Ultimately, this prospective data collection will allow us to determine prognostic factors for successful corneal transplantation and create an algorithm to guide clinical practice based on real world outcomes. The second objective is to collect and create a database of historical, de-identified optical coherence topography (OCT) and corneal topography images to ultimately develop artificial intelligence (AI) based diagnostic and prognostic algorithms for corneal disease and surgery.

Conditions

  • Corneal Disease
  • Endothelial Corneal Dystrophy
  • Corneal Transplant Failure
  • Corneal Transplant Rejection

Interventions

DIAGNOSTIC_TEST

Optical Coherence Tomography

Non-invasive imaging test that use light waves to take cross-section pictures of the eye.

Sponsors & Collaborators

  • Nitin Vaswani

    lead OTHER

Principal Investigators

  • Priya M Mathews, MD · Keratoplasty Alliance International

  • Nitin G Vaswani, MD · Keratoplasty Alliance International

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-12
Primary Completion
2024-08-15
Completion
2024-08-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06101017 on ClinicalTrials.gov