The Gastric HormonE BioMarkers of Preneoplastic Lesions Study
NCT06085677 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 600
Last updated 2023-10-17
Summary
The goal of the study is to understand whether blood levels of hormones produced or metabolized in the stomach reflect the health of the stomach lining.
Specifically the study will determine whether the concentration of ghrelin, gastrin, pepsinogens and vitamin B12 reflect the condition of the stomach lining. Hormone concentrations for people with normal/mild gastritis will be compared to people with long-term inflammation of the stomach (chronic atrophic gastritis), and people with pre-cancerous cellular changes (intestinal metaplasia).
Conditions
- Stomach Neoplasm
- Chronic Atrophic Gastritis
- Intestinal Metaplasia
Sponsors & Collaborators
-
University College, London
collaborator OTHER -
University of Oxford
collaborator OTHER -
University of Copenhagen
collaborator OTHER -
Imperial College London
lead OTHER
Principal Investigators
-
Gwen Murphy, PhD MPH · Imperial College Dublin
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-11-04
- Primary Completion
- 2024-09-02
- Completion
- 2024-09-02
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