Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis

Summary

A placebo-controlled randomized controlled trial exploring the effect of intraarticular steroids, saline or an occupational therapy intervention in inflammatory carpometacarpal-1 osteoarthritis

Conditions

• Osteoarthritis Thumb

Interventions

DRUG

Injection of triamcinolone acetonide into the CMC-1 joint

intraarticular injection with triamcinolone acetonide

BEHAVIORAL

Multimodal Occupational therapy for CMC-1 joint OA

Patient education, instructions about hand exercises, orthosis and training

DRUG

Placebo

Intraarticular injection with saline

Sponsors & Collaborators

• Vestre Viken Hospital Trust

  collaborator OTHER

• Helse Stavanger HF

  collaborator OTHER_GOV

• Haugesund Rheumatism Hospital

  collaborator OTHER

• St. Olavs Hospital

  collaborator OTHER

• Nordlandssykehuset HF

  collaborator OTHER

• Diakonhjemmet Hospital

  lead OTHER

Principal Investigators

• Ida Kristin Haugen, MD, PhD · Diakonhjemmet Hospital

• Marte Ingeborg Sæther · Martina Hansens Hospital

• Elisabet Esperø · Haugesund Rheumatism Hospital

• Katrine Brække Norheim · Helse Stavanger HF

• Mari Hoff · St. Olavs Hospital

• Göran Karlsson · Nordland Hospital

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

40 Years

Max Age

85 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-11-03

Primary Completion

2027-01-31

Completion

2028-10-31

Countries

• Norway

Study Locations