MedTrace Logo

Potential Role of Inflammasome NLRP3 And IL-1B Gene Expression in COVID-19 Patients: Impact of Ferretin and D -Dimer.

NCT06080750 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 75

Last updated 2023-10-12

No results posted yet for this study

Summary

2.1 Study the role of NLRP3 inflammasome in COVID-19 patients. 2.2 Study the gene expression of NLRP3 and IL-1β in blood samples of COVID-19 patients and compare to apparently healthy subjects.

2.3 Correlation between NLRP3, IL-1β, IL-6 and severity of the disease. 2.4 Impact of ferritin and D-dimer on inflammasome componnets NLRP3, IL-1β IL-6 .

Conditions

  • Inflammasome NLRP3 And IL-1B Gene Expression in COVID-19 Patients

Interventions

GENETIC

Quantitative Real Time Polymerase chain reaction (qRT-PCR)

to study gene expression of NLRP3 inflammasome and IL-1B in blood

DIAGNOSTIC_TEST

ELISA and colorimeter

IL-6 and total LDH

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Ayat A Sayed, M.D · associate professor

  • Mona A AlBaz, M.D · Professor

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2024-01-01
Completion
2025-01-01

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06080750 on ClinicalTrials.gov