Impact of Therapeutic Plasma Exchange on RNA Biomarker Expression Levels in Alzheimer's Patients

Multiple Ascending Dose Study of TC-5619 in Healthy Elderly Subjects and Subjects With Alzheimer's Disease

NCT01254448 ·Status: COMPLETED ·Phase: PHASE1

A Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease

NCT01561053 ·Status: COMPLETED ·Phase: PHASE2/PHASE3

Evaluation of [18F]RO6958948 as Tracer for Positron Emission Tomography (PET) Imaging of Tau Burden in Alzheimer's Disease Participants

NCT02792179 ·Status: COMPLETED ·Phase: PHASE1

Exploratory Clinical Study and Validation of Blood Biomarkers for Alzheimer's Disease

NCT07294586 ·Status: COMPLETED

A Community-Based Screening Program to Identify Participants at High Risk for Amyloid Pathology

NCT06043700 ·Status: ACTIVE_NOT_RECRUITING

A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)

NCT06402838 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2

Biodistribution of [11C]PIB in Patients With Risk Factors for Alzheimer's Disease

NCT03089827 ·Status: ENROLLING_BY_INVITATION

Returning Research Results That Indicate Risk of Alzheimer Disease Dementia to Healthy Participants in Longitudinal Studies

NCT04699786 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA

Alzheimer's Plasma Extension

NCT06416072 ·Status: ACTIVE_NOT_RECRUITING

A Study of LY2886721 in Healthy Participants and Participants Diagnosed With Alzheimer's Disease

NCT01807026 ·Status: COMPLETED ·Phase: PHASE1

TRC-PAD Program: In-Clinic Trial-Ready Cohort

NCT04004767 ·Status: COMPLETED

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild Alzheimer's Disease

NCT01689233 ·Status: COMPLETED ·Phase: PHASE3

A Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Anti-Abeta (MABT5102A) in Patients With Alzheimer's Disease

NCT00736775 ·Status: COMPLETED ·Phase: PHASE1

Next-Generation alzheImer'S Therapeutics

NCT06372587 ·Status: RECRUITING ·Phase: NA

A Clinical Trial of AAV2-BDNF Gene Therapy in Early Alzheimer's Disease and Mild Cognitive Impairment

NCT05040217 ·Status: RECRUITING ·Phase: PHASE1

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

NCT05262023 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2

Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia Taking Stable Donepezil Treatment (MK-1167-007)

NCT06285240 ·Status: COMPLETED ·Phase: PHASE1

A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

NCT03131453 ·Status: TERMINATED ·Phase: PHASE2/PHASE3

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Behavioral Variant Frontotemporal Dementia (bvFTD)

NCT01626378 ·Status: COMPLETED ·Phase: PHASE3

Efficacy and Safety of Plasma Exchange With 5% Albumin in Beta-amyloid Peptide Clearance in Cerebral Spinal Fluid

NCT00742417 ·Status: COMPLETED ·Phase: PHASE2

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.

NCT04623242 ·Status: COMPLETED ·Phase: PHASE2/PHASE3

A Long Term Extension Study to Assess the Safety of TB006 in Participants With Alzheimer's Disease

NCT05476783 ·Status: TERMINATED ·Phase: PHASE2

Efficacy and Safety of MK-1942 as an Adjunct Therapy in Participants With Mild to Moderate Alzheimer's Disease Dementia (MK-1942-008)

NCT05602727 ·Status: TERMINATED ·Phase: PHASE2

Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease

NCT02547818 ·Status: COMPLETED ·Phase: PHASE3

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

NCT06064890 ·Status: RECRUITING ·Phase: PHASE1/PHASE2