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Prognostic Value of Tumor Deposits for Patients With Papillary Thyroid Carcinoma

NCT06051838 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 541

Last updated 2023-09-25

No results posted yet for this study

Summary

Tumor deposits (TD), nodules in the peritumoral adipose tissue with no architectural residue of lymph node, which is a definition often being confusing to the extranodal extension (ENE), have been described in several malignancies and linked to a worse prognosis. In gastric cancer and colon cancer, TD and ENE should be distinguished and collected separately in 8th AJCC manual. However, in thyroid cancer, TD as a collection variable was absence in both the 8th AJCC manual and the 2015 ATA guideline. This is a study that revealed the presence of TD by reviewing a large number of papillary thyroid carcinoma (PTC) specimens and explored its prognostic value by constructing a nomogram to accurately predict disease-free survival in PTC patients.

Conditions

  • Exploring the Prognostic Value of Tumor Deposits PTC Patients

Interventions

PROCEDURE

surgery

if the patients is TD positive, we recommond careful surgery and pathological examination.

Sponsors & Collaborators

  • Nanfang Hospital, Southern Medical University

    lead OTHER

Principal Investigators

  • Shangtong Lei · Nanfang Hospital, Southern Medical University

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-01
Primary Completion
2023-02-28
Completion
2023-03-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06051838 on ClinicalTrials.gov