MedTrace Logo

Diagnostic Importance of the C-reactive Protein From Blood and Saliva in Children With Acute Appendicitis

NCT06051825 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2023-09-25

No results posted yet for this study

Summary

Diagnosing acute appendicitis in children is still a challenge even for experienced clinicians. Failure to recognize this acute condition can result in perforation, with consequent peritonitis, or misdiagnosis can result in negative appendectomies. C-reactive protein in blood can be elavated in children with acute appendicitis. The aim of this research is to compare the diagnostic value of C-reactive protein from the blood and saliva of children with acute appendicitis and to prove wheter the analysis of biomarker from saliva as a minimally invasive procedure can be sufficient for diagnosis.

Conditions

  • Acute Appendicitis

Interventions

DIAGNOSTIC_TEST

Blood specimen collection for C-reactive protein (CRP) and WBC (white blood cells). Saliva specimen collection for analysis of CRP levels

Blood analysis of CRP and WBC levels Saliva analysis of CRP levels

Sponsors & Collaborators

  • University Hospital of Split

    lead OTHER

Principal Investigators

  • Zenon Pogorelić, PhD.Prof · University Hospital of Split

Eligibility

Min Age
5 Years
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-11-01
Primary Completion
2024-10-30
Completion
2024-11-30

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06051825 on ClinicalTrials.gov