A Phase 1 Study of NM6603 in Advanced Solid Tumors
NCT06046066 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 17
Last updated 2026-05-07
Summary
This study is to assess the MTD and RP2D of NM6603 in adult patients with advanced solid tumors.
Conditions
Interventions
- DRUG
-
NM6603
NM6603 is an orally available investigational small molecule indicated for the treatment of solid malignancies including, but not limited to breast, liver, pancreatic, colorectal, cervical, melanoma and lung cancers.
Sponsors & Collaborators
-
NucMito Pharmaceuticals Co. Ltd.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-08-31
- Primary Completion
- 2025-04-25
- Completion
- 2025-04-25
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Nab-Paclitaxel/STI-3031 Complex (AP160-Complex) for the Treatment of Advanced or Metastatic Solid Tumors
NCT05653661 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Phase 1 Multicenter Open-label Study to Evaluate the Safety Tolerability and PK of MEDI0680 (AMP-514) in Subjects With Advanced Malignancies
NCT02013804 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Study Evaluating H1710 for Injection in Participants With Advanced Solid Tumors
NCT06992713 ·Status: RECRUITING ·Phase: PHASE1
-
Trial to Study the Safety of Intravenous MNK-010 in Advanced Solid Tumors
NCT02040558 ·Status: TERMINATED ·Phase: PHASE1
-
BMS-214662 in Treating Patients With Advanced Solid Tumors
NCT00004877 ·Status: COMPLETED ·Phase: PHASE1
-
Intravenous T3011 Given as a Single Agent and in Combination With Other Therapy in Subjects With Advanced Solid Tumors
NCT04780217 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors
NCT06403436 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
SMP-3124LP in Adults With Advanced Solid Tumors
NCT06526819 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of MK2206 in Locally Advanced or Metastatic Solid Tumors (2206-007)
NCT01071018 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Dose Escalation and Dose Expansion Trial of NP-101 in Patients With Solid Tumors
NCT06563375 ·Status: RECRUITING ·Phase: PHASE1
-
A Study Evaluating the Safety, Tolerance and Anti-tumor Activity of HBM1020 in Subjects With Advanced Solid Tumors
NCT05824663 ·Status: COMPLETED ·Phase: PHASE1
-
TTP607 in Refractory Solid Malignancies
NCT00939172 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Clinical Study of 9MW2821 in Subjects With Advanced Malignant Solid Tumors
NCT05216965 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
MAX-10181 in Patients With Advanced Solid Tumor
NCT05196360 ·Status: UNKNOWN ·Phase: PHASE1
-
Study of the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Antitumor Activity of KN046 in Subjects With Advanced Solid Tumors
NCT03529526 ·Status: UNKNOWN ·Phase: PHASE1
-
A Phase 1 Study of KBP-5209 in Patients With Advanced Solid Tumors
NCT02442414 ·Status: COMPLETED ·Phase: PHASE1
-
The Safety and Pharmacokinetics Preliminary Efficacy of IMP7068 in Patients With Advanced Solid Tumors
NCT04768868 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of MK0731 in Patients With Advanced Solid Tumors (0731-002)(COMPLETED)
NCT00104364 ·Status: COMPLETED ·Phase: PHASE1
-
Study of HS-20105 for Injection in Patients With Advanced Solid Tumors.
NCT06144723 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of mRNA-4106 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Solid Tumors
NCT06880549 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06307795 ·Status: RECRUITING ·Phase: PHASE1
-
First in Human Study of M1069 in Advanced Solid Tumors
NCT05198349 ·Status: TERMINATED ·Phase: PHASE1
-
A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors
NCT06248411 ·Status: RECRUITING ·Phase: PHASE1
-
A Microdose Study of TTX-MC138-NODAGA-Cu64 in Subjects With Advanced Solid Tumors
NCT05908773 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies
NCT05023486 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2