The Effect of Switching the H1-antagonist Clemastine to Cetirizine in Premedication Regimens During Paclitaxel Treatment
NCT06039137 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 395
Last updated 2024-09-25
Summary
In this study the effect of substituting clemastine IV to cetirizine PO on the occurence of hypersensitivity reactions during paclitaxel chemotherapy will be investigated.
Conditions
Interventions
- DRUG
-
Cetirizine
Subjects were treated with a paclitaxel premedication regimen which contained oral cetirizine instead of intravenous clemastine
- DRUG
-
Clemastine IV
Subjects were treated with paclitaxel premedication containing clemastine 2 mg IV
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Roelof van Leeuwen, PharmD, PhD · Erasmus Medical Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-01
- Primary Completion
- 2023-04-27
- Completion
- 2023-10-31
Countries
- Netherlands
Study Locations
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