Trial Outcomes & Findings for EHR-integrated rUTI Texting Platform (NCT NCT06035601)
NCT ID: NCT06035601
Last Updated: 2026-08-20
Results Overview
Antibiotics prescribed for patients when 1) urine culture is negative and/or urine microscopy has pyuria \< 10 WBC/HPF, 2) asymptomatic bacteriuria is present, or 3) there is no urine testing and no urinary symptoms.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
102 participants
Primary outcome timeframe
3 months
Results posted on
2026-08-20
Participant Flow
Participant milestones
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
|---|---|---|
|
Overall Study
STARTED
|
51
|
51
|
|
Overall Study
COMPLETED
|
51
|
51
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
EHR-integrated rUTI Texting Platform
Baseline characteristics by cohort
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
n=51 Participants
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
n=51 Participants
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
Total
n=102 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
67 years
n=5 Participants
|
66 years
n=109 Participants
|
66 years
n=133 Participants
|
|
Sex: Female, Male
Female
|
51 Participants
n=5 Participants
|
51 Participants
n=109 Participants
|
102 Participants
n=133 Participants
|
|
Sex: Female, Male
Male
|
0 Participants
n=5 Participants
|
0 Participants
n=109 Participants
|
0 Participants
n=133 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
2 Participants
n=5 Participants
|
3 Participants
n=109 Participants
|
5 Participants
n=133 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
49 Participants
n=5 Participants
|
48 Participants
n=109 Participants
|
97 Participants
n=133 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
0 Participants
n=109 Participants
|
0 Participants
n=133 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=5 Participants
|
0 Participants
n=109 Participants
|
0 Participants
n=133 Participants
|
|
Race (NIH/OMB)
Asian
|
0 Participants
n=5 Participants
|
0 Participants
n=109 Participants
|
0 Participants
n=133 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=5 Participants
|
0 Participants
n=109 Participants
|
0 Participants
n=133 Participants
|
|
Race (NIH/OMB)
Black or African American
|
6 Participants
n=5 Participants
|
14 Participants
n=109 Participants
|
20 Participants
n=133 Participants
|
|
Race (NIH/OMB)
White
|
39 Participants
n=5 Participants
|
33 Participants
n=109 Participants
|
72 Participants
n=133 Participants
|
|
Race (NIH/OMB)
More than one race
|
6 Participants
n=5 Participants
|
4 Participants
n=109 Participants
|
10 Participants
n=133 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
0 Participants
n=109 Participants
|
0 Participants
n=133 Participants
|
|
Social Vulnerability Index
|
.18 index score
n=5 Participants
|
.33 index score
n=109 Participants
|
.23 index score
n=133 Participants
|
|
Body Mass Index
|
26.8 kg/m2
n=5 Participants
|
29.8 kg/m2
n=109 Participants
|
28 kg/m2
n=133 Participants
|
PRIMARY outcome
Timeframe: 3 monthsAntibiotics prescribed for patients when 1) urine culture is negative and/or urine microscopy has pyuria \< 10 WBC/HPF, 2) asymptomatic bacteriuria is present, or 3) there is no urine testing and no urinary symptoms.
Outcome measures
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
n=51 Participants
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
n=51 Participants
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
|---|---|---|
|
Rate of Unnecessary Antibiotics
|
6 Participants
|
15 Participants
|
SECONDARY outcome
Timeframe: 3 monthsStanford self-efficacy for managing chronic disease 6-item score (mean score range 1-10 with mean 1 indicating less self-efficacy)
Outcome measures
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
n=51 Participants
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
n=51 Participants
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
|---|---|---|
|
Patient Self-efficacy
|
7.8 score on a scale
Standard Deviation 1.8
|
7.3 score on a scale
Standard Deviation 1.7
|
SECONDARY outcome
Timeframe: 3 monthsPatient Global Impression of Improvement score (score range 1-7 with 1 indicating very much better).
Outcome measures
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
n=51 Participants
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
n=51 Participants
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
|---|---|---|
|
Patient Satisfaction: Patient Global Impression of Improvement Score
|
1.90 score on a scale
Standard Deviation .984
|
2.67 score on a scale
Standard Deviation 1.089
|
SECONDARY outcome
Timeframe: 3 monthsEuroQol 5-Dimension 5-Level (EQ-5D-5L) score which assesses how good or bad their health is on a scale from 0 to 100 with a higher score indicating better health status.
Outcome measures
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
n=51 Participants
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
n=51 Participants
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
|---|---|---|
|
Healthcare-related Quality of Life: EQ-5D-5L Score
|
76.5 score on a scale
Standard Deviation 16.8
|
74.0 score on a scale
Standard Deviation 19.8
|
SECONDARY outcome
Timeframe: 3 monthsRecurrent Urinary Tract Infection Impact Questionnaire score. Scores range from 0 to 100, with greater scores indicating greater overall UTI symptom and pain severity.
Outcome measures
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
n=51 Participants
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
n=51 Participants
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
|---|---|---|
|
Healthcare-related Quality of Life: Recurrent UTI Impact Questionnaire Score
|
24.2 score on a scale
Standard Deviation 21.3
|
22.0 score on a scale
Standard Deviation 19.0
|
SECONDARY outcome
Timeframe: 3 monthsCombined number of phone calls, secure messages per UTI episode
Outcome measures
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
n=51 Participants
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
n=51 Participants
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
|---|---|---|
|
Healthcare Utilization
|
0.7 messages and phone calls
Standard Deviation 1.2
|
5.5 messages and phone calls
Standard Deviation 11.5
|
SECONDARY outcome
Timeframe: 3 monthsNumber of antibiotic prescriptions given for UTI episodes
Outcome measures
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
n=51 Participants
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
n=51 Participants
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
|---|---|---|
|
Antibiotic Prescriptions
|
0.43 number of antibiotic prescriptions
Standard Deviation 0.67
|
0.76 number of antibiotic prescriptions
Standard Deviation 1.18
|
SECONDARY outcome
Timeframe: 3 monthsMedication Adherence Self-Report Inventory score (score range 0-100 with 0 indicating no medication usage)
Outcome measures
| Measure |
Electronic Health Record (EHR)-Integrated Texting Platform
n=51 Participants
Patients will be enrolled into a texting platform for the management of recurrent UTI.
EHR-integrated texting platform (Urotrust): • An evidence-based algorithm that provides symptom triage and clinical guidance during an episode of acute UTI
* Evidence-based prevention education material on recurrent UTIs
* 5 standing orders for urinalysis and urine culture in the EHR upon enrollment
* Standard-of-care management for recurrent UTI
|
Usual Care
n=51 Participants
Patients will receive usual care through their providers.
Usual care: • Standard-of-care management of recurrent UTI (phone calls and/or secure EHR messages for acute symptoms) and follow up visits as determined by patients and their providers.
|
|---|---|---|
|
Patient Medication Compliance
|
76.6 score on a scale
Standard Deviation 35.2
|
78.7 score on a scale
Standard Deviation 35.0
|
Adverse Events
Electronic Health Record (EHR)-Integrated Texting Platform
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Usual Care
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place