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Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment

NCT06033274 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 800

Last updated 2025-09-10

No results posted yet for this study

Summary

The field of transcatheter tricuspid valve replacement (TTVR) is rapidly emerging and data on this topic are scarce. Particularly, little is known about which patients are at greatest risk of procedural complications, such as the timing and onset of conduction disturbances necessitating permanent pacemaker implantation, and how such patients are managed. On this background, the TRIPLACE Registry - an investigator-initiated global multicenter registry - is aimed at better understanding the safety and efficacy of orthotopic TTVR.

Conditions

  • Tricuspid Regurgitation

Interventions

DEVICE

Transcatheter Tricuspid Valve Replacement

All patients undergoing Transcatheter Tricuspid Valve Replacement for native tricuspid valve disease

Sponsors & Collaborators

  • The Cleveland Clinic

    collaborator OTHER

  • University of Toronto

    collaborator OTHER

  • University Hospital, Bordeaux

    collaborator OTHER

  • Montefiore Medical Center

    lead OTHER

Principal Investigators

  • Andrea Scotti, MD · Montefiore Medical Center

  • Azeem Latib, MD · Montefiore Medical Center

  • Rishi Puri, MD · The Cleveland Clinic

  • Neil Fam, MD · St. Michaels Hospital

  • Thomas Modine, MD · University Hospital, Bordeaux

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-05
Primary Completion
2026-08-31
Completion
2026-08-31

Countries

  • United States
  • Canada
  • Denmark
  • France
  • Germany
  • Italy
  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06033274 on ClinicalTrials.gov