A Study of REC-4881 in Participants With Cancers Which Have an AXIN1 or APC Mutation
NCT06005974 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 18
Last updated 2026-02-23
Summary
This is a multi-center, open-label study to investigate the safety, efficacy and pharmacokinetics of REC-4881 (12 mg PO daily doses) for the treatment of participants with unresectable locally advanced or metastatic solid tumors with AXIN1 or APC mutation.
Conditions
- AXIN1 Gene Mutation
- APC Gene Mutation
- Solid Tumor
Interventions
- DRUG
-
REC-4881 4mg capsules
Sponsors & Collaborators
-
Recursion Pharmaceuticals Inc.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-01-15
- Primary Completion
- 2025-02-24
- Completion
- 2025-02-24
- FDA Drug
- Yes
Countries
- United States
Study Locations
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