Raman Spectroscopy for Liver Tumours Following Liver Surgery
NCT05995990 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19
Last updated 2023-08-16
Summary
The aim of the proposed research is to develop a quick and reliable method for automated evaluation of tissue sections for residual tumour in histology specimens following liver surgery. This advanced technology will enable assessment of liver tumours and resection margins following liver surgery. The technology is based on Raman spectroscopy (RS) and multivariate spectral analysis to produce 2-dimensional biochemical images that can reliably separate the spectral signal of liver tumours from surrounding normal tissue.
Conditions
- Colorectal Cancer Metastatic
Interventions
- DEVICE
-
Raman Spectrometry
Laboratory technique of Raman Spectrometry
Sponsors & Collaborators
-
Nottingham University Hospitals NHS Trust
lead OTHER
Principal Investigators
-
Dhanwant Gomez, FRCS · Nottingham University Hospitals NHS Trust
-
Ioan Notingher, PhD · University of Nottingham
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-11-25
- Primary Completion
- 2021-12-31
- Completion
- 2021-12-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
Detecting Colorectal Cancer With Liver Metastatic Lesions Using Novel Precise Imaging Tools
NCT06935149 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Multimodal Assessment of Liver Volume and Function
NCT03140917 ·Status: COMPLETED
-
Modelling Internal Hepatic Movement With an External Abdominal Marker
NCT00299299 ·Status: UNKNOWN
-
Circulating Tumor Cells in mCRC for Liver Resection
NCT03295591 ·Status: UNKNOWN
-
Risk Factors, Prognosis, and Potential Chemoprevention Drugs in Patients With Recurrent Hepatocellular Carcinoma After Curative Surgeries: a Nationwide Retrospective Cohort Study and a Multi-center Prospective Cohort Analysis
NCT05990959 ·Status: RECRUITING
-
Applying Artificial Intelligence to Optimize Early-stage Hepatocellular Carcinoma Treatment Based on Multi-modal Image
NCT05627297 ·Status: RECRUITING
-
Chemotherapy and Tumor Clearance in Hepatic Resections for Colorectal Liver Metastases.
NCT05273489 ·Status: COMPLETED
-
Detection and Automatic Segmentation of Liver Nodules in Patients With Colorectal Adenocarcinoma
NCT04834596 ·Status: UNKNOWN
-
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer
NCT00899210 ·Status: COMPLETED
-
Ablation vs Resection of Colorectal Cancer Liver Metastases
NCT05129787 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Predicting Survival After Surgical Resection for the Entire Spectrum of Anatomically Resectable HCC
NCT06294808 ·Status: COMPLETED
-
Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot Study
NCT06964425 ·Status: RECRUITING ·Phase: NA
-
Evaluation of Metabolic Activity of Liver Metastases by FDG-PET Scanning
NCT00184782 ·Status: UNKNOWN ·Phase: NA
-
Liver Transplantation for Non-resectable Colorectal Liver Metastases: Translational Research
NCT05398380 ·Status: RECRUITING ·Phase: NA
-
Feasibility Study of Neoadjuvant Chemotherapy Modified FOLFOX6 for Resectable Liver Metastases of Colorectal Cancers
NCT00594529 ·Status: UNKNOWN ·Phase: PHASE2
-
Precision Medicine for Colorectal Cancer Liver Metastasis Guided by Multi-omics Data Under the Umbrella Theory
NCT04525807 ·Status: UNKNOWN
-
Dynamic ctDNA Detection for Colorectal Cancer Liver Metastases
NCT06404593 ·Status: COMPLETED
-
Survival Analysis of Surgical Resection Versus Observation in Patients With Initially uHCC Achieving CR After Systemic Therapy
NCT07290764 ·Status: ENROLLING_BY_INVITATION
-
Metastatic Colorectal Cancer Liver Metastases Outcomes After Resin 90Y Microsphere Radioembolization in the USA Evaluation Project
NCT01815879 ·Status: UNKNOWN
-
Utility of Intra-operative Image Guidance System for Missing Metastases
NCT02806037 ·Status: COMPLETED
-
To Identify KRAS Gene and Safe Margin in Association With Outcome in Colorectal Liver Metastases Following Ultrasound-guided Radiofrequency Ablation
NCT04417010 ·Status: UNKNOWN
-
French Assessment of MRD by Liquid Biopsies in Colorectal With Liver Metastasis Patients (FRENCH.MRD.CRLM)
NCT06287723 ·Status: NOT_YET_RECRUITING
-
Next Generation Sequencing in Intrahepatic Cholangiocarcinoma
NCT02184871 ·Status: UNKNOWN
-
Impact of Positron Emission Tomography Imaging Prior to Liver Resection for Colorectal Adenocarcinoma Metastases
NCT00265356 ·Status: COMPLETED ·Phase: PHASE3
-
Safety, Efficacy, and Dosing of Stereotactic Radiosurgery for Hepato-cellular Carc/Colo-rectal Liver Metastases
NCT01528878 ·Status: COMPLETED ·Phase: NA