SIRT for Potentially Resectable HCC
NCT05994859 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2023-09-14
Summary
This study is conducted to evaluate the efficacy and safety of Y-90 selective internal radiation therapy (SIRT) in patients with potentially resectable hepatocellular carcinoma (HCC).
Conditions
Interventions
- PROCEDURE
-
SIRT
The patients will receive 1-2 sessions of SIRT. If the patients have invasive tumors, extensive liver involvement or vascular invasion, systematic treatment will be added.
Sponsors & Collaborators
-
Second Affiliated Hospital of Guangzhou Medical University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-08-10
- Primary Completion
- 2026-08-09
- Completion
- 2027-02-09
Countries
- China
Study Locations
More Related Trials
-
Sintilimab Plus Bevacizumab and SIRT for Intermediate-advanced HCC
NCT06397222 ·Status: RECRUITING ·Phase: PHASE2
-
Observational Study for SIR-Spheres Therapy for the Treatment of HCC Patients in China
NCT06712017 ·Status: ENROLLING_BY_INVITATION
-
Lenvatinib Plus SIRT vs Lenvatinib in TACE-Refractory HCC
NCT06904196 ·Status: RECRUITING ·Phase: PHASE2
-
The Efficacy of Transarterial Chemoinfusion (TAI) Combine Stereotactic Body Radiation Therapy (SBRT) in Unresectable Hepatocellular Carcinoma (HCC)
NCT03851887 ·Status: UNKNOWN ·Phase: PHASE2
-
Preoperative Stereotactic Body Radiotherapy (SBRT) Followed by Hepatectomy for Centrally Located Hepatocellular Carcinoma: a Prospective, Single-center, Phase I Study
NCT05598060 ·Status: UNKNOWN ·Phase: NA
-
Study of SIR-Spheres Plus Sorafenib as 1st Line Treatment for Non-resectable Primary Hepatocellular Carcinoma (HCC)
NCT00712790 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Pathological Results of Aggressive Hepatocellular Carcinomas Treated Using SIRT
NCT05045573 ·Status: COMPLETED
-
SIRT or TACE Plus Lenvatinib and PD-(L)1 Inhibitor in High Burden HCC
NCT06916546 ·Status: COMPLETED
-
A Study of the Safety and Antitumoral Efficacy of Nivolumab After SIRT for the Treatment of Patients With HCC
NCT03380130 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment for Bile Duct Cancer in the Liver
NCT02167711 ·Status: COMPLETED ·Phase: PHASE2
-
Ablation Combined With PD-1 in HCC: Phase II Study
NCT04652440 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Evaluating the Effects of Selective Treatment Utilizing Flex-dosing for Unresectable HCC With Y90 SIR-Spheres
NCT04903548 ·Status: COMPLETED
-
Study to Compare Selective Internal Radiation Therapy (SIRT) Versus Sorafenib in Locally Advanced Hepatocellular Carcinoma (HCC)
NCT01135056 ·Status: UNKNOWN ·Phase: PHASE3
-
Stereotactic Body Radiation Therapy for the Safety and Prognosis of Small Intrahepatic Recurrent HCC
NCT05596630 ·Status: RECRUITING ·Phase: NA
-
SIRT Versus cTACE for Unresectable HCC (CHANCE2506)
NCT06909708 ·Status: RECRUITING ·Phase: NA
-
Non-inferiority Study of Unresectable Hepatocelluar Carcinoma Receiving Stereotactic Radiotherapy Combined With Hepatic Arterial Chemoembolization Compared With Conversion Hepatectomy
NCT05057104 ·Status: UNKNOWN
-
Radiotherapy as an Adjuvant Therapy After Radiofrequency Ablation for Hepatocellular Carcinoma
NCT00557024 ·Status: UNKNOWN ·Phase: PHASE4
-
Selective Internal Radiation Therapy and Capecitabine (Chemotherapy) Treatment for Liver Cancer
NCT05265208 ·Status: RECRUITING ·Phase: PHASE2
-
Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients
NCT04736121 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry)
NCT05967143 ·Status: RECRUITING
-
SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma
NCT02807181 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Comparison of SBRT and SIRT With Combination IO for Locally-advanced, Unresectable HCCs (BIIRTH)
NCT07293468 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Efficacy and Safety of Yttrium-90 Microspheres Selective Internal Radiotherapy Combined with Immune Checkpoint Inhibitors and Anti-angiogenesis Drugs Sequential HAIC for Hepatocellular Carcinoma
NCT06867432 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Stereotactic Body Radiotherapy for Unresectable Hepatocellular Carcinoma
NCT01910909 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Ablative Radiotherapy for Hepatocellular Carcinoma ≤ 5 cm
NCT01825824 ·Status: UNKNOWN ·Phase: PHASE2