Evaluation of Digit Tip and Split Skin Donor Site Transcriptome
NCT05991765 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 75
Last updated 2023-08-15
Summary
Regrowth of amputated fingertips presents a unique regenerative healing process in mammals, with subcutaneous volume regrowth, restoration of the dactylogram, and suppression of scar formation. In addition, wound healing from split-thickness donor sites shows almost scar-free healing. Transcriptome analysis is necessary to better understand the specific healing mechanisms of these two wound entities. Since no data are available to date, this study aims to fill the gap.
Conditions
- Digit Tip Wound
- Split Skin Donor Site
Interventions
- OTHER
-
Digit Tip Wound
Digit Tip Wound Exudate Sample Collected while Dressing Change
- OTHER
-
Split Skin Donor Site Wound
Split Skin Donor Site Wound Exudate Sample while Dressing Change
Sponsors & Collaborators
-
University Hospital Schleswig-Holstein
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-06-01
- Primary Completion
- 2022-04-30
- Completion
- 2023-12-31
Countries
- Germany
Study Locations
More Related Trials
-
Influence of a Silicone Gel (Dermatix®) on Thoracic Scar Formation After Harvesting of Autologous Rib Cartilage
NCT00565552 ·Status: UNKNOWN ·Phase: NA
-
Manual Implantation of Full-Thickness Skin Microcolumns
NCT05223998 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Study to Evaluate the Efficacy of an Acellular Dermal Template for the Treatment of Full Thickness Skin Defects
NCT02373566 ·Status: COMPLETED ·Phase: NA
-
Trial to Compare Intra-individually the Efficacy and Tolerance of Oleogel-S10 Versus Moist Wound Healing Dressing Alone in Accelerating the Epithelialization of Split Thickness Skin Graft Donor Sites
NCT01294254 ·Status: COMPLETED ·Phase: PHASE2
-
A Single-stage Bilayered Skin Reconstruction With Glyaderm®
NCT06249971 ·Status: COMPLETED ·Phase: NA
-
Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting
NCT01974583 ·Status: COMPLETED
-
Trial of Zesteem (Estradiol) in Healing of Split Thickness Skin Graft Donor Sites
NCT00426972 ·Status: COMPLETED ·Phase: PHASE3
-
The Dorsal Homodigital Island Flap Based on the Dorsal Branch of the Digital Artery: A Review of 171 Cases
NCT01871103 ·Status: COMPLETED ·Phase: NA
-
Autologous Point-of-Care Adipose Therapy: Recent Injury
NCT06857448 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Repair of Multiple Finger Defects Using the Dorsal Homodigital Island Flaps
NCT01767727 ·Status: COMPLETED ·Phase: NA
-
Cutaneous Microcirculation After Plasma Therapy
NCT02417818 ·Status: COMPLETED ·Phase: NA
-
Negative Pressure Wound Therapy Compared to Traditional Care After Skin Grafting
NCT03649308 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Evaluation of the Product Properties of Individualized 3D-compression Garments to Treat Scars
NCT03664505 ·Status: COMPLETED ·Phase: NA
-
Oleogel-S10 in Wound Healing of Split-Thickness Skin Graft Donor Sites (BSG-12)
NCT01807650 ·Status: COMPLETED ·Phase: PHASE3
-
Autologous Fat Grafting Beneath Penile Split Thickness Skin Graft Placement During Penile Reconstruction
NCT07316491 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Scarring in Stratagraft-treated vs. Autograft-treated Burn Wounds: a Clinical and Histological Investigation
NCT04896346 ·Status: UNKNOWN
-
The Use of Integra in Coverage of Radial Forearm Free Flap Donor Site Defect
NCT02980601 ·Status: TERMINATED ·Phase: NA
-
Evaluation of the Postoperative Effect of Expanded Pedicled Deltopectoral Flap to Repair the Facial-Cervical Scars
NCT03735641 ·Status: UNKNOWN
-
Mesenchymal Stem Cell-derived Pleiotropic Factor in the Treatment of Donor Sites
NCT04234750 ·Status: UNKNOWN ·Phase: PHASE1
-
The Improving Effect of Autologous Stromal Vascular Fraction (SVF) in Adipose Tissue on Skin Grafting
NCT02546882 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Adipose Tissue Extract and Platelet-rich Plasma Use for Wound Healing
NCT02799290 ·Status: COMPLETED ·Phase: PHASE2
-
Use of Epidermal Expansion System for Epidermal Grafting on Hypopigmented Skin and Surgical Wounds
NCT01590329 ·Status: UNKNOWN ·Phase: NA
-
The Comparison of Thick Split-thickness Skin Graft Versus Thin Split-thickness Skin Graft
NCT05571904 ·Status: UNKNOWN ·Phase: NA
-
The Dermisgraft Epithelialization and Late Scar Healing
NCT05189743 ·Status: COMPLETED ·Phase: NA
-
Evaluation of the Use of Minced Skin Grafts for Promoting Donor Site Wound Healing After Split-Thickness Skin Grafting
NCT06488612 ·Status: RECRUITING ·Phase: NA