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MDMA-assisted Brief Cognitive Behavioral Conjoint Therapy for PTSD

NCT05979844 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2025-12-08

No results posted yet for this study

Summary

The goal of this pilot trial is to examine the preliminary effectiveness of MDMA-facilitated bCBCT for improving chronic PTSD and relationship functioning in a sample of veterans and their intimate partners seeking care within the VA San Diego Healthcare System.

Conditions

  • PTSD
  • Relational Problems

Interventions

DRUG

3,4-methylenedioxymethamphetamine (MDMA)

2 MDMA sessions; PTSD+ Veteran partner only

BEHAVIORAL

Brief Cognitive Behavioral Conjoint Therapy (bCBCT)

8 bCBCT sessions; Both partners

Sponsors & Collaborators

  • Healing Breakthrough

    collaborator UNKNOWN

  • Lykos Therapeutics

    collaborator INDUSTRY

  • San Diego Veterans Healthcare System

    collaborator FED

  • Dr. Leslie Morland

    lead FED

Principal Investigators

  • Leslie Morland · San Diego Veterans Healthcare System

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-06
Primary Completion
2025-11-14
Completion
2025-11-14
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05979844 on ClinicalTrials.gov