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Medical Stone Expulsive Therapy for Acutely Obstructed Ureteric Calculi

NCT05977647 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 240

Last updated 2025-08-20

No results posted yet for this study

Summary

As a first treatment option for small-size ureteric stones, α-blockers are now being used for medical expulsive therapy (MET) instead of invasive procedures. There is high evidence of the therapeutic benefit of α-blockers in the treatment of Distal ureteric stone (DUS); also endorsed by international guidelines.

However, limited data is available worldwide, on the effect of silodosin to treat DUS. A multi-center study is needed to confirm the efficacy and safety of therapy.

Conditions

  • Ureteric Stone of Lower Third of Ureter

Interventions

DRUG

Tamsulosin Oral Capsule

Patient will be enrolled in one of study arm through randomization.

Sponsors & Collaborators

  • Getz Pharma

    lead INDUSTRY

Principal Investigators

  • Salman El Khalid, MBBS · The Kidney Centre

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-09-01
Primary Completion
2025-05-30
Completion
2025-06-30

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05977647 on ClinicalTrials.gov