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LSD-Perceptual-Choice-Study

NCT05976698 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-03-14

No results posted yet for this study

Summary

The aim of the study is to characterize the effects of low doses of LSD (d-lysergic acid diethylamide) on behavioral and neural indicators of feedback and feedforward signaling in perceptual decision-making.

Conditions

  • LSD Reaction

Interventions

DRUG

LSD 10 μg

0.5 h after the start of each study session the participants will be administered 10 μg LSD per os in the form of vials containing 1ml 20% EtOH (ethanol).

DRUG

LSD 20 μg

0.5 h after the start of each study session the participants will be administered 20 μg LSD per os in the form of vials containing 1ml 20% EtOH.

DRUG

Placebo

0.5 h after the start of each study session the participants will be administered placebo per os in the form of vials containing 1ml 20% EtOH.

Sponsors & Collaborators

  • University of Basel

    collaborator OTHER

  • University Psychiatric Clinics Basel

    collaborator NETWORK

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Philipp Sterzer, Prof. Dr. · University Psychiatric Clinics Basel

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-02-26
Primary Completion
2025-02-25
Completion
2025-02-25

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05976698 on ClinicalTrials.gov