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Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening

NCT05975736 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2025-02-19

No results posted yet for this study

Summary

Brief Summary

A task like breast cancer screening (mammography) can be described as a "hybrid search" task. In basic visual search tasks, observers search for a target among distractors that are not the target. In hybrid search, observers search for two or more target types. In mammography, observers are searching for masses, calcifications ("calcs"), and some other signs of cancer like architectural distortion. In this experiment, the investigators have created a simulated version of mammography where non-expert (non-radiologist) observers can look for simulated masses and calcs. There are two types of stimuli, a 2D version (like an x-ray) and a 3D version (like the output of Digital Breast Tomosynthesis - DBT). The question that is being asked is whether it is better to ask about masses and calcs separately (first one, then the other) or to just let observers look for both at the same time.

Conditions

Interventions

BEHAVIORAL

Search only for masses

Participants search the simulated mammogram for simulated masses.

BEHAVIORAL

Search only for calcifications

Participants search the simulated mammogram for simulated calcifications.

BEHAVIORAL

Search for both together

Search the simulated mammogram for both simulated masses and simulated calcifications at the same time.

BEHAVIORAL

Search for one after the other

Search the simulated mammogram for first for simulated masses and then for simulated calcifications sequentially (or vice versa).

Sponsors & Collaborators

  • Brigham and Women's Hospital

    lead OTHER

Principal Investigators

  • Jeremy M Wolfe, PhD · Brigham and Women's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-09-01
Primary Completion
2027-09-01
Completion
2028-09-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05975736 on ClinicalTrials.gov