Trial Outcomes & Findings for Improving DFU Outcomes: Early Detection of Foot Ulcers Using Novel Technology (NCT NCT05968924)

NCT ID: NCT05968924

Last Updated: 2026-04-30

Results Overview

Participant adherence to use of SmartMat will be quantified by automated data collection. Adherence is defined as having conducted \>3 days foot scans per week (foot scans/week) over the six-month period. The median number of scans/week over a six-month period is reported.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

20 participants

Primary outcome timeframe

Up to six months following intervention

Results posted on

2026-04-30

Participant Flow

The study cohort was drawn from a regional referral center for diabetic foot complications, receiving referrals from vascular surgery, endocrinology, emergency room, primary care physicians, other podiatrists, orthopedics, infectious disease and home care nursing teams across multiple Montefiore Medical Center campus locations. The cohort was intended to reflect the broad racial, ethnic, and socioeconomic diversity of the Bronx, consistent with the borough's overall demographics.

Participant milestones

Participant milestones
Measure
High Risk Diabetic Foot Ulcer (DFU)
Podimetrics smart map Podimetrics SmartMat: Participants receive training for stepping on SmartMat each day for 6 months. Monthly phone calls will be conducted to assess foot health and mat.
Overall Study
STARTED
20
Overall Study
COMPLETED
19
Overall Study
NOT COMPLETED
1

Reasons for withdrawal

Reasons for withdrawal
Measure
High Risk Diabetic Foot Ulcer (DFU)
Podimetrics smart map Podimetrics SmartMat: Participants receive training for stepping on SmartMat each day for 6 months. Monthly phone calls will be conducted to assess foot health and mat.
Overall Study
Death
1

Baseline Characteristics

Improving DFU Outcomes: Early Detection of Foot Ulcers Using Novel Technology

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
High Risk Diabetic Foot Ulcer (DFU)
n=20 Participants
Podimetrics smart map Podimetrics SmartMat: Participants receive training for stepping on SmartMat each day for 6 months. Monthly phone calls will be conducted to assess foot health and mat.
Age, Continuous
62.7 years
STANDARD_DEVIATION 8.0 • n=14 Participants
Sex: Female, Male
Female
3 Participants
n=14 Participants
Sex: Female, Male
Male
17 Participants
n=14 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
8 Participants
n=14 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
9 Participants
n=14 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
3 Participants
n=14 Participants
Race (NIH/OMB)
American Indian or Alaska Native
1 Participants
n=14 Participants
Race (NIH/OMB)
Asian
0 Participants
n=14 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=14 Participants
Race (NIH/OMB)
Black or African American
12 Participants
n=14 Participants
Race (NIH/OMB)
White
4 Participants
n=14 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=14 Participants
Race (NIH/OMB)
Unknown or Not Reported
3 Participants
n=14 Participants
Region of Enrollment
United States
20 Participants
n=14 Participants

PRIMARY outcome

Timeframe: Up to six months following intervention

Participant adherence to use of SmartMat will be quantified by automated data collection. Adherence is defined as having conducted \>3 days foot scans per week (foot scans/week) over the six-month period. The median number of scans/week over a six-month period is reported.

Outcome measures

Outcome measures
Measure
High Risk Diabetic Foot Ulcer (DFU)
n=19 Participants
Podimetrics smart map Podimetrics SmartMat: Participants receive training for stepping on SmartMat each day for 6 months. Monthly phone calls will be conducted to assess foot health and mat.
Adherence to Use of SmartMat
6.4 number of foot scans/week
Interval 5.6 to 6.8

SECONDARY outcome

Timeframe: Up to six months following intervention

Use of health care facilities will be enumerated based on the number of participants who presented for care over the course of the study. This will include patient visits to the Emergency Room (ER), podiatrist, internist, walk in clinic, and other health care facilities. This outcome will be based on participant self-reporting of visits. The total number of participants who visited a health care facility is summarized.

Outcome measures

Outcome measures
Measure
High Risk Diabetic Foot Ulcer (DFU)
n=19 Participants
Podimetrics smart map Podimetrics SmartMat: Participants receive training for stepping on SmartMat each day for 6 months. Monthly phone calls will be conducted to assess foot health and mat.
Use of Health Care Facilities
6 Participants

SECONDARY outcome

Timeframe: Up to six months following intervention

The number of participants who developed DFU during the course of the study is summarized. Diagnosis of DFU was be based on a physical exam.

Outcome measures

Outcome measures
Measure
High Risk Diabetic Foot Ulcer (DFU)
n=19 Participants
Podimetrics smart map Podimetrics SmartMat: Participants receive training for stepping on SmartMat each day for 6 months. Monthly phone calls will be conducted to assess foot health and mat.
Occurrence of Diabetic Foot Ulcer (DFU)
5 Participants

POST_HOC outcome

Timeframe: Up to six months following intervention

The number of re-engagement calls per participant over the 6-month study period is summarized using basic descriptive statistics. Participants were called each month to determine if there was any diabetic foot ulcer development or utilization of health care facilities (corresponding study outcome measures). Increases in foot temperature (i.e., increase in 2.2 degrees Celsius over two consecutive uses between and of six contralaterally sites), a marker for early ulcer, also triggered a call to the study participant.

Outcome measures

Outcome measures
Measure
High Risk Diabetic Foot Ulcer (DFU)
n=19 Participants
Podimetrics smart map Podimetrics SmartMat: Participants receive training for stepping on SmartMat each day for 6 months. Monthly phone calls will be conducted to assess foot health and mat.
The Number of Re-engagement Calls Per Participant Over the 6-month Study Period
2 calls per participant
Interval 0.0 to 3.0

Adverse Events

High Risk Diabetic Foot Ulcer (DFU)

Serious events: 6 serious events
Other events: 16 other events
Deaths: 1 deaths

Serious adverse events

Serious adverse events
Measure
High Risk Diabetic Foot Ulcer (DFU)
n=20 participants at risk
Podimetrics smart map Podimetrics SmartMat: Participants receive training for stepping on SmartMat each day for 6 months. Monthly phone calls will be conducted to assess foot health and mat.
Skin and subcutaneous tissue disorders
Hospitalization
5.0%
1/20 • Number of events 1 • Approximately six months
General disorders
Hospitalization
25.0%
5/20 • Number of events 5 • Approximately six months

Other adverse events

Other adverse events
Measure
High Risk Diabetic Foot Ulcer (DFU)
n=20 participants at risk
Podimetrics smart map Podimetrics SmartMat: Participants receive training for stepping on SmartMat each day for 6 months. Monthly phone calls will be conducted to assess foot health and mat.
Infections and infestations
Increased Foot Temperature
60.0%
12/20 • Number of events 14 • Approximately six months
Skin and subcutaneous tissue disorders
Diabetic Foot Ulcer
25.0%
5/20 • Number of events 5 • Approximately six months
Skin and subcutaneous tissue disorders
Pre-ulcerative hyperkeratosis
5.0%
1/20 • Number of events 1 • Approximately six months
Infections and infestations
Osteomyelitis
5.0%
1/20 • Number of events 1 • Approximately six months

Additional Information

Dr. Johanna Daily

Montefiore Medical Center

Phone: 7188780020

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place