Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients
NCT05968066 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2508
Last updated 2025-12-03
Summary
The goal of this woldwide observational study is to investigate various aspects of fluid and vasopressor therapy in critically ill invasively ventilated patients. The main questions it aims to answer are:
* What is the global current practice of fluid and vasopressor therapy?
* What are associations between this practice and clinical outcomes?
Participating intensive care units will gather detailed information about fluid and vasopressor therapy prescribed to participants. Participating intensive care units will also gather information about participant outcomes such as duration of invasive ventilation, length of stay and mortality
Conditions
- Fluid Therapy
- Vasopressor Therapy
- Critical Illness
- Invasive Ventilation
Sponsors & Collaborators
-
Mahidol Oxford Tropical Medicine Research Unit
collaborator OTHER -
Amsterdam UMC, location VUmc
collaborator OTHER -
University Hospital, Antwerp
collaborator OTHER -
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
lead OTHER
Principal Investigators
-
Pieter R. Tuinman, MD · Amsterdam UMC, location VUmc
-
Frederique Paulus, Professor · Amsterdam UMC, location AMC
-
Marcus J. Schultz, Professor · Mahidol Oxford Tropical Medicine Research Unit
Eligibility
- Min Age
- 16 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-12-01
- Primary Completion
- 2025-09-23
- Completion
- 2025-10-22
Countries
- Netherlands
Study Locations
More Related Trials
-
Personalized Hemodynamic Therapy in Patients Undergoing High-risk Surgery
NCT02834377 ·Status: COMPLETED ·Phase: NA
-
Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation
NCT05014581 ·Status: RECRUITING ·Phase: PHASE3
-
Cerebral Autoregulation in Non Neurological Critical Patients.
NCT01731106 ·Status: TERMINATED
-
Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy
NCT00526331 ·Status: COMPLETED ·Phase: PHASE4
-
Non-invasive Prediction of Fluid and Noradrenaline Responsiveness Using the Carotid Wave Intensity.
NCT06197321 ·Status: COMPLETED
-
Preload Dependence During Prone Position In ARDS Patients
NCT01965574 ·Status: COMPLETED ·Phase: NA
-
Assessment of Fluid Responsiveness in Patients After Cardiac Surgery
NCT02571465 ·Status: COMPLETED
-
Fluid Day Spanish Observational Study
NCT03630744 ·Status: UNKNOWN
-
Complications Related to Transpulmonary Thermodilution
NCT04319965 ·Status: UNKNOWN
-
A Systematic Echography During Intubation Procedure to Predict Cardiovascular Collapse
NCT03184207 ·Status: COMPLETED
-
Surrogate of Adequate Perfusion: Bladder Tissue Oxygen Monitoring
NCT03935477 ·Status: UNKNOWN
-
Feasibility of Extended Non-invasive Haemodynamic Monitoring in the PACU
NCT04814966 ·Status: COMPLETED
-
Prediction Model of the Blood Pressure Response to the Administration of Fluids in Abdominal Surgery Using the Pram Method.
NCT04594174 ·Status: UNKNOWN
-
The Effect of Perioperative Cardiac Output-guided GDT on Oxygen Delivery, Consumption, and Microcirculatory Perfusion
NCT05090254 ·Status: COMPLETED ·Phase: NA
-
Clot Formation and Coagulation Factors Consumption in the Clearing Fluid After Arterial Catheter Blood Sampling.
NCT06349551 ·Status: COMPLETED
-
The Effect of Norepinephrine on the Development of Pressure Injury
NCT06860308 ·Status: COMPLETED
-
EFFECT OF VASOPRESSORS ON FLUID CHALLENGE PERSISTENCE AN OBSERVATIONAL STUDY IN PATIENTS UNDERGOING LAPAROTOMY.
NCT04934345 ·Status: UNKNOWN
-
Fluid Responsiveness Evaluation by AbdomiNal Compression in Kids Based on the STARLING Concept
NCT02505646 ·Status: COMPLETED
-
Hemodynamic Monitoring, Positive Inotropic and Vasoactive Drugs During Cardiac Surgery (EMOA)
NCT02571920 ·Status: COMPLETED
-
Diagnostic Value of Passive Leg Raise Induced Changes in Carotid Artery Flow Time to Predict Fluid Responsiveness in Critically Ill Patients
NCT02789124 ·Status: COMPLETED ·Phase: NA
-
Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®
NCT07022314 ·Status: NOT_YET_RECRUITING
-
Effect of SVV-guided Fluid Therapy on Outcomes After Major Abdominal Surgery
NCT03940144 ·Status: COMPLETED ·Phase: NA
-
Preoperative Ultrasound-based Protocol for Optimization of Fluid Therapy to Prevent Early Intraoperative Hypotension
NCT05171608 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Different Priming Solutions Effects on Microcirculation, Oxidative Stress and Morbidity in Cardiovascular Surgery Patients
NCT02501681 ·Status: COMPLETED ·Phase: PHASE4
-
Prone Positioning in ARDS: Predicting Neurological Complications Via Cerebral Hemodynamics
NCT06967285 ·Status: RECRUITING