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Sensory Modulation Dysfunction and Posttraumatic Stress Disorder

NCT05967962 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 248

Last updated 2026-03-10

No results posted yet for this study

Summary

To explore the role of sensory modulation dysfunction (SMD) (i.e., a neurodevelopmental state altering the sensory perception, severely interfering with daily function) as a risk factor for posttraumatic stress disorder (PTSD), its co-occurring pain, and impeded cognitive functions, following exposure to combat trauma.

Conditions

Interventions

BEHAVIORAL

The Trauma Film Paradigm

Trauma film paradigm is a well-known, validated and established procedure that produces reactions similar to those generated by trauma, and that is often used in research to predict susceptibility for peritraumatic and posttraumatic reactions. In this study the trauma film paradigm will be utilized to simulate combat exposure. The two groups of participants will undergo the trauma film paradigm by watching 16 min traumatic combat scenes vs. non-traumatic movie scenes, respectively. Participants will be given standardized instructions (i.e., ''Imagine you are present at the scene"; "Do not close your eyes").

BEHAVIORAL

non-traumatic (neutral) film

non-traumatic (neutral) film

Sponsors & Collaborators

  • Tel Aviv University

    lead OTHER

Principal Investigators

  • Tami Bar-Shalita, PhD · Tel Aviv University

  • Yael Lahav, PhD · Tel Aviv University

  • Michal Lifshitz, MD · Israel Defense Forces

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
28 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-05-01
Primary Completion
2024-12-31
Completion
2025-02-28

Countries

  • Israel

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05967962 on ClinicalTrials.gov