Trial Outcomes & Findings for Fully Remote Use of IpsiHand Device in Hemiparetic Stroke (NCT NCT05965713)

NCT ID: NCT05965713

Last Updated: 2026-08-12

Results Overview

Assessment tool of upper extremity motor function. Lowest score 0, highest score 66.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

109 participants

Primary outcome timeframe

12 weeks

Results posted on

2026-08-12

Participant Flow

Participant milestones

Participant milestones
Measure
Home Based BCI Rehabilitation (BCI)
Participants were instructed to use the device for home-based therapy sessions 1 hour per day, 5 days per week, for a continuous 12 weeks.
Home Exercise Rehabilitation Regimen Program (HEP)
The program consisted of a customized set of range of motion and functional tasks targeting the hand, wrist, elbow, and shoulder. Participants were instructed to complete 1 hour of home exercise per day, 5 days per week, over the course of 12 weeks.
Overall Study
STARTED
43
42
Overall Study
COMPLETED
37
25
Overall Study
NOT COMPLETED
6
17

Reasons for withdrawal

Reasons for withdrawal
Measure
Home Based BCI Rehabilitation (BCI)
Participants were instructed to use the device for home-based therapy sessions 1 hour per day, 5 days per week, for a continuous 12 weeks.
Home Exercise Rehabilitation Regimen Program (HEP)
The program consisted of a customized set of range of motion and functional tasks targeting the hand, wrist, elbow, and shoulder. Participants were instructed to complete 1 hour of home exercise per day, 5 days per week, over the course of 12 weeks.
Overall Study
Protocol Violation
3
0
Overall Study
Withdrawal by Subject
3
17

Baseline Characteristics

Subjects with Protocol Deviations after randomization were excluded from analysis

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Home Based BCI Rehabilitation (BCI)
n=37 Participants
Participants were instructed to use the device for home-based therapy sessions 1 hour per day, 5 days per week, for a continuous 12 weeks.
Home Exercise Rehabilitation Regimen Program (HEP)
n=25 Participants
The program consisted of a customized set of range of motion and functional tasks targeting the hand, wrist, elbow, and shoulder. Participants were instructed to complete 1 hour of home exercise per day, 5 days per week, over the course of 12 weeks.
Total
n=62 Participants
Total of all reporting groups
Age, Customized
Age
58.1 Years
STANDARD_DEVIATION 15.7 • n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
53.1 Years
STANDARD_DEVIATION 16.6 • n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
56.4 Years
STANDARD_DEVIATION 16.2 • n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
Sex: Female, Male
Female
13 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
11 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
24 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
Sex: Female, Male
Male
24 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
14 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
38 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
Race/Ethnicity, Customized
White
28 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
21 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
49 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
Race/Ethnicity, Customized
Black
4 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
2 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
6 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
Race/Ethnicity, Customized
Asian
1 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
1 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
2 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
Race/Ethnicity, Customized
Other/Unknown
4 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
1 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
5 Participants
n=1 Participants • Subjects with Protocol Deviations after randomization were excluded from analysis
Upper Extremity Fugl-Meyer
26.3 Units on a scale
STANDARD_DEVIATION 17.9 • n=1 Participants • Participants with protocol deviations or with missing data after enrollment were excluded from evaluation
26.7 Units on a scale
STANDARD_DEVIATION 14.4 • n=1 Participants • Participants with protocol deviations or with missing data after enrollment were excluded from evaluation
26.5 Units on a scale
STANDARD_DEVIATION 16.4 • n=1 Participants • Participants with protocol deviations or with missing data after enrollment were excluded from evaluation

PRIMARY outcome

Timeframe: 12 weeks

Population: Noted Protocol Deviations and missing Completion timepoints excluded subjects from per protocol analysis

Assessment tool of upper extremity motor function. Lowest score 0, highest score 66.

Outcome measures

Outcome measures
Measure
Home Based BCI Rehabilitation (BCI)
n=31 Participants
Participants were instructed to use the device for home-based therapy sessions 1 hour per day, 5 days per week, for a continuous 12 weeks.
Home Exercise Rehabilitation Regimen Program (HEP)
n=21 Participants
The program consisted of a customized set of range of motion and functional tasks targeting the hand, wrist, elbow, and shoulder. Participants were instructed to complete 1 hour of home exercise per day, 5 days per week, over the course of 12 weeks.
Upper Extremity Fugl-Meyer (UEFM)
32.6 Units on a scale
Standard Deviation 18.3
28.1 Units on a scale
Standard Deviation 16.6

Adverse Events

Home Exercise Rehabilitation Regimen Program (HEP)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Home Based BCI Rehabilitation (BCI)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Seth Wilk, PhD, Chief Innovation Officer

Neurolutions, Inc.

Phone: 1 833 438 4774

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place