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Clinical Study of TCR-like CAR-T Cell Targeted MSLN in the Treatment of Ovarian Cancer

NCT05963100 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2025-04-02

No results posted yet for this study

Summary

The goal of this clinical trial is to test TCR-like CAR-T in the Treatment of MSLN positive Ovarian Cancer. The main question it aims to answer are: the safety and efficacy of TCR-like CAR-T in the Treatment of MSLN positive Ovarian Cancer.

Conditions

  • Safety and Efficacy of TCR-like CAR-T

Interventions

BIOLOGICAL

TCR-like CAR-T

intravenous drip of TCR-like CAR-T with indicated doses

Sponsors & Collaborators

  • Zhongda Hospital

    lead OTHER

Principal Investigators

  • Yang Shen, PhD · Zhongda Hospital

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-08-07
Primary Completion
2026-05-16
Completion
2026-05-16

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05963100 on ClinicalTrials.gov