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HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma

NCT05962242 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2026-02-05

No results posted yet for this study

Summary

The study will evaluate the safety and effectiveness of a lower than standard dose of radiation for definitive or adjuvant treatment of head and neck squamous cell carcinomas.

Conditions

  • Squamous Cell Carcinoma of the Oropharynx

Interventions

RADIATION

Radiation Therapy

External Beam Radiation to Head and Neck

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Chris McLaughlin, M.D. · UVA

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-06-28
Primary Completion
2027-11-01
Completion
2029-11-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05962242 on ClinicalTrials.gov