Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
NCT05961839 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 66
Last updated 2025-09-22
Summary
The purpose of this study is to evaluate safety and tolerability and to determine the maximum tolerated dose (MTD) and/or recommended dose (RD) of SGR-2921.
Conditions
- Acute Myeloid Leukemia
- High-Risk and Very High-Risk Myelodysplastic Syndromes
Interventions
- DRUG
-
SGR-2921
SGR-2921 will be administered orally.
Sponsors & Collaborators
-
Schrödinger, Inc.
lead INDUSTRY
Principal Investigators
-
Daniel Weiss, M.D. · Schrödinger, Inc.
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-09-27
- Primary Completion
- 2025-08-14
- Completion
- 2025-09-09
- FDA Drug
- Yes
Countries
- United States
Study Locations
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