Trial Outcomes & Findings for Impact of a Telenovela/Soap Opera for HIV Prevention in Latinas (NCT NCT05929482)

Impact of a Telenovela/Soap Opera for HIV Prevention in Latinas

Change in the proportion of sexual episodes (oral, vaginal, or anal intercourse) in which condoms were used in the last month. Change from Baseline was calculated to Month 1 and Month 7.

PrEP awareness will be measured as the number of participants who self-report whether they know about PrEP medication (dichotomous question: yes/no).

Changes in PrEP access will be measured as the number of participants who report that they have access to PrEP (dichotomous question: yes/no)

Changes in PrEP use will be measured as the number of participants that have familarity with PrEP and self-report whether they currently use PrEP medication (dichotomous question: yes/no)

Changes in HIV testing will be measured as the number of participants who reported to have been tested for HIV in the last month.

The online website will track the number of participants who complete intervention content (four 10-minute episodes of the telenovela episode).

The number of participants who completed all study assessment timepoints from start to finish.

Changes in Self-Efficacy for condom use will be measured using the HIV self-efficacy for condom use survey. Scores range from 7-28. A higher score indicates a higher level of self-efficacy for condom use.

The effects of emotional response (ER), Narrative engagement (NE) and Self-efficacy (SE) on PrEP awareness will be estimated. ER, NE and SE will be measured using the scales reported on outcomes 15-17 and PrEP awareness will be measured as described in outcome 3. A logistic regression model will be conducted including group assignment (intervention or control), ER, NE and SE as predictors of PrEP awareness. The estimated odd ratios of each predictor will be reported. Odds ratio greater than 1 will indicate higher occurrence of PrEP awareness given exposure to the predictors.

Changes in substance abuse will be measured with the Substance abuse behaviors scale. Scores range from 6-36. A higher score represents a higher use of substances.

Changes in IPV will be measured using the revised Conflict Tactics Scale to measure women's self-reported IPV in the previous 3 months (e.g., your partner insulted you). Scores range from 24-72 points. A higher score indicates higher levels of IPV.

Changes in depression will be measured with the Patient Health screening in primary care and other health settings. Scores range from 5-27. A higher score indicates more depressive symptoms.

Substance abuse (SA), intimate partner violence (IPV) and depression measured with the scales described in outcome 21-23 will be tested as predictors of condom use (measured as described outcome 1). A linear regression model will be conducted. The estimated regression coefficients (beta) of each predictor will be reported. Higher coefficients indicate a stronger effect of these variables on condom use.

Substance abuse (SA), intimate partner violence (IPV) and depression measured with the scales described in outcome 21-23 will be tested as predictors of HIV testing (measured as described outcome 9). A logistic regression model will be conducted. The estimated odds ratio of each independent variable will be reported. Odds ratio greater than 1 will indicate higher occurrence of HIV testing given exposure to the predictors.

Substance abuse (SA), intimate partner violence (IPV) and depression measured with the scales described in outcome 21-23 will be tested as predictors of PrEP awareness (measured as described outcome 3). A logistic regression model will be conducted. The estimated odds ratio of each predictor will be reported. Odds ratio greater than 1 will indicate higher occurrence of PrEP awareness given exposure to the predictors.

The effects of emotional response (ER), Narrative engagement (NE) and Self-efficacy (SE) on HIV testing will be estimated. ER, NE and SE will be measured using the scales reported on outcomes 15-17 and HIV testing will be measured as described in outcome 9. A logistic regression model will be conducted including group assignment (intervention or control), ER, NE and SE as predictors of HIV testing. The estimated odd ratios of each predictor will be reported. Odds ratio greater than 1 will indicate higher occurrence of HIV testing given exposure to the predictors.

The effects of emotional response (ER), Narrative engagement (NE) and Self-efficacy (SE) on condom use will be estimated. ER, NE and SE will be measured using the scales reported on outcomes 15-17 and condom use will be measured as described in outcome 1. A lineal regression model including group assignment (intervention or control), ER, NE and SE as predictors of condom use will be conducted. The estimated regression coefficients (beta) of each independent variable will be reported. Higher estimated regression coefficients represent higher effects of these variables on condom use.

Changes in narrative engagement (NE) will be measured with the Perception of Narrative Performance Scale, which measures three dimensions of engagement: interest, realism, and identification. Scores range from 9-36. A higher score indicates a higher level of engagement.

Changes in emotional Response (ER) will be measured with the International Positive and Negative Affect Schedule Short Form (IPANAS-SF). Scores range from 10-50. Higher scores indicate the tendency to experience a positive and negative mood.