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Fluorescence Imaging of the Parathyroid Glands of Children

NCT05917067 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 23

Last updated 2025-01-30

No results posted yet for this study

Summary

The aim of this study is to develop a standardized and user-independent imaging workflow model for autofluorescence and quantified fluorescence angiography with Indocyanine Green (ICG) of the parathyroid glands of children. For this purpose, all pediatric patients will undergo thyroid surgery with the use of autofluorescence and quantified ICG-fluorescence.

This study could be the first step in reducing the rate of postoperative hypocalcemia in children, by using fluorescence angiography during pediatric thyroid surgery.

Conditions

  • Childhood Thyroid Gland Carcinoma
  • Thyroid Diseases

Interventions

DIAGNOSTIC_TEST

Fluorescence imaging of the parathyroid glands of children

Patients that participate in this study will always receive standard care. For the purpose of this study, the camera settings (i.e. camera distance to the operating field, switching of OR-lights, and angle of the camera on the operating field) and ICG-protocol (i.e. dose, injection speed) will be standardized among the participating centers in order to generate an homogeneous data set for quantification of the fluorescence signal intensity.

Sponsors & Collaborators

  • Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

    lead OTHER

Principal Investigators

  • Joep Derikx, MD, PhD · Amsterdam UMC - Emma Children's Hospital

Eligibility

Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-01
Primary Completion
2024-10-01
Completion
2024-12-01

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05917067 on ClinicalTrials.gov