Trial Outcomes & Findings for Start the Conversation: Evaluating Implementation of a Multi-level PrEP Initiative for Black Cisgender Women in Nola (NCT NCT05909176)

NCT ID: NCT05909176

Last Updated: 2026-07-10

Results Overview

Total number of women overall and number of Black cisgender women with whom GYN residents start the conversation about PrEP (pre-exposure prophylaxis)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

51 participants

Primary outcome timeframe

Up to 18 months (from month 5 to month 22)

Results posted on

2026-07-10

Participant Flow

Patients were assessed by OBGYN residents for PrEP (pre-exposure prophylaxis) candidacy and initiated PrEP discussions with patients who may benefit from PrEP.

Participants in the pre-intervention phase were not considered enrolled. Participants are not randomized into study arms; instead, there are two distinct study populations. Group 1 includes patients from OB/GYN resident clinics, with activities divided into two phases: Phase 1 (months 5-14) and Phase 2 (months 15-22). Patients who were determined by OBGYN residents to not benefit from PrEP were excluded. Group 2 consists of individuals engaged through a social media campaign during months 15-22.

Participant milestones

Participant milestones
Measure
Combined Care Model Only (Months 5-14)
Phase 1 includes implementation of the combined-care model: training for GYN residents to (1) start a conversation about PrEP with patients at the LSU GYN residency clinic at UMCNO, and (2) have a discussion about PrEP follow-up at either the LSU GYN residency clinic at UMCNO or a PrEP clinic, for 10 months (months 5-14).
Combined Care + Social Media (Months 15-22)
Phase 2 includes the addition of social media campaign about Black women and PrEP in the NOLA area for 8 months (months 15-22) plus the continued implementation of the combined-care model at LSU GYN residency clinic at UMCNO (months 15-22).
Overall Study
STARTED
41
10
Overall Study
COMPLETED
41
10
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Start the Conversation: Evaluating Implementation of a Multi-level PrEP Initiative for Black Cisgender Women in Nola

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Combined Care Model Only (Months 5-14)
n=41 Participants
GYN Residency Training (Phase I): The combined care model will be implemented and during months 5-14.
Combined Care + Social Media (Months 15-22)
n=10 Participants
Social Media Campaign + GYN Residency Training (Phase II): The social media campaign will be implemented along with the combined care model in months 15-22.
Total
n=51 Participants
Total of all reporting groups
Age, Continuous
33.29 years
STANDARD_DEVIATION 10.11 • n=9 Participants
33.80 years
STANDARD_DEVIATION 11.45 • n=27 Participants
33.39 years
STANDARD_DEVIATION 10.26 • n=267 Participants
Sex: Female, Male
Female
41 Participants
n=9 Participants
10 Participants
n=27 Participants
51 Participants
n=267 Participants
Sex: Female, Male
Male
0 Participants
n=9 Participants
0 Participants
n=27 Participants
0 Participants
n=267 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
16 Participants
n=9 Participants
3 Participants
n=27 Participants
19 Participants
n=267 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
25 Participants
n=9 Participants
7 Participants
n=27 Participants
32 Participants
n=267 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=9 Participants
0 Participants
n=27 Participants
0 Participants
n=267 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=9 Participants
0 Participants
n=27 Participants
0 Participants
n=267 Participants
Race (NIH/OMB)
Asian
1 Participants
n=9 Participants
0 Participants
n=27 Participants
1 Participants
n=267 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=9 Participants
0 Participants
n=27 Participants
0 Participants
n=267 Participants
Race (NIH/OMB)
Black or African American
22 Participants
n=9 Participants
6 Participants
n=27 Participants
28 Participants
n=267 Participants
Race (NIH/OMB)
White
2 Participants
n=9 Participants
0 Participants
n=27 Participants
2 Participants
n=267 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=9 Participants
0 Participants
n=27 Participants
0 Participants
n=267 Participants
Race (NIH/OMB)
Unknown or Not Reported
16 Participants
n=9 Participants
4 Participants
n=27 Participants
20 Participants
n=267 Participants
Region of Enrollment
United States
41 Participants
n=9 Participants
10 Participants
n=27 Participants
51 Participants
n=267 Participants

PRIMARY outcome

Timeframe: Up to 18 months (from month 5 to month 22)

Population: All patients with whom GYN residents started a conversation about PrEP in each phase were included.

Total number of women overall and number of Black cisgender women with whom GYN residents start the conversation about PrEP (pre-exposure prophylaxis)

Outcome measures

Outcome measures
Measure
Combined Care Only (Months 5-14)
n=41 Participants
GYN Residency Training (Phase I): The combined care model will be implemented and during months 5-14.
Combined Care + Social Media (Months 15-22)
n=10 Participants
Social Media Campaign + GYN Residency Training (Phase II): The social media campaign will be implemented along with the combined care model in months 15-22.
Number of Women Engaged in Conversation
All women
41 Participants
10 Participants
Number of Women Engaged in Conversation
Black cisgender women
22 Participants
6 Participants

PRIMARY outcome

Timeframe: Up to 18 months (from month 5 to month 22)

Population: All patients with whom GYN residents started a conversation about PrEP in each phase were included.

Total number of women initiating PrEP (Pre-exposure Prophylaxis) at the LSU (Louisiana State University) GYN clinic (or after referral to a PrEP clinic).

Outcome measures

Outcome measures
Measure
Combined Care Only (Months 5-14)
n=41 Participants
GYN Residency Training (Phase I): The combined care model will be implemented and during months 5-14.
Combined Care + Social Media (Months 15-22)
n=10 Participants
Social Media Campaign + GYN Residency Training (Phase II): The social media campaign will be implemented along with the combined care model in months 15-22.
Total Number of Women Initiating PrEP
Latina ethnicity
1 Participants
1 Participants
Total Number of Women Initiating PrEP
Black race
3 Participants
2 Participants
Total Number of Women Initiating PrEP
Declined to answer about ethnicity and race
0 Participants
1 Participants

SECONDARY outcome

Timeframe: Up to 18 months (from month 5 to month 22)

Population: Participants who started on PrEP.

Outcome measures

Outcome measures
Measure
Combined Care Only (Months 5-14)
n=8 Participants
GYN Residency Training (Phase I): The combined care model will be implemented and during months 5-14.
Combined Care + Social Media (Months 15-22)
Social Media Campaign + GYN Residency Training (Phase II): The social media campaign will be implemented along with the combined care model in months 15-22.
Number of Women Choosing Follow-up Care at the LSU (Louisiana State University) GYN Resident Clinic Versus Transition to a Local PrEP (Pre-exposure Prophylaxis) Provider
PrEP clinic
2 Participants
Number of Women Choosing Follow-up Care at the LSU (Louisiana State University) GYN Resident Clinic Versus Transition to a Local PrEP (Pre-exposure Prophylaxis) Provider
GYN clinic
6 Participants

SECONDARY outcome

Timeframe: Up to 18 months (from month 5 to month 22)

Population: Participants who made a follow-up appointment.

Outcome measures

Outcome measures
Measure
Combined Care Only (Months 5-14)
n=8 Participants
GYN Residency Training (Phase I): The combined care model will be implemented and during months 5-14.
Combined Care + Social Media (Months 15-22)
Social Media Campaign + GYN Residency Training (Phase II): The social media campaign will be implemented along with the combined care model in months 15-22.
Overall Number of Women Who Initiated PrEP and Completed a Follow-up Appointment
3 Participants

SECONDARY outcome

Timeframe: Up to 8 months (from month 15 to month 22)

Population: Social Media Campaign participants. The social media campaign will be implemented along with the combined care model in months 15-22.

Measured by verifiable clicks to the LaHub Website from social media campaign pages. Data reflects the total number of "clicks" across all social media campaign pages.

Outcome measures

Outcome measures
Measure
Combined Care Only (Months 5-14)
n=14 social media campaign pages
GYN Residency Training (Phase I): The combined care model will be implemented and during months 5-14.
Combined Care + Social Media (Months 15-22)
Social Media Campaign + GYN Residency Training (Phase II): The social media campaign will be implemented along with the combined care model in months 15-22.
Total Number of Contacts With the LaHub Website
392 clicks

OTHER_PRE_SPECIFIED outcome

Timeframe: Up to 18 months (from month 5 to month 22)

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Up to 18 months (from month 5 to month 22)

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Up to 18 months (from month 5 to month 22)

Outcome measures

Outcome data not reported

Adverse Events

Start the Conversation Package - Implementation Phase I

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Start the Conversation Package - Implementation Phase II

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Amy Corneli, Ph.D.

Duke University

Phone: 919-668-9238

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place