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Dry Eye Symptom Mitigation by Oral Intake of Probiotics

NCT05906381 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 88

Last updated 2025-09-26

No results posted yet for this study

Summary

This study investigates whether the oral intake of a probiotics capsule product may relieve dry eye symptoms. Participants will be aged between 20 - 65 years of age, with confirmed diagnosis of dry eye status. The participants will be assessed for several parameters and asked to take 1 probiotics capsule per day for 35 days. The parameters will include ocular surface health, tear volume, tear quality, intraocular pressure, tear osmolarity and serum biochemical test. After the 35 days are completed, the participants will be assessed again for the same parameters.

Conditions

  • Dry Eye

Interventions

DIETARY_SUPPLEMENT

Probiotics

A specific probiotics capsule product, containing Streptococcus thermophilus will be given to participants for oral intake for 35 days.

DIETARY_SUPPLEMENT

Placebo

A specific capsule product, containing microcrystalline cellulose will be given to participants for oral intake for 35 days.

Sponsors & Collaborators

  • Nutrarex Biotech Co., Ltd.

    collaborator UNKNOWN

  • Chung Shan Medical University

    lead OTHER

Principal Investigators

  • David Pei-Cheng Lin · Chung Shan Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-13
Primary Completion
2023-08-31
Completion
2023-12-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05906381 on ClinicalTrials.gov