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Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension

NCT05881252 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1003

Last updated 2025-07-28

No results posted yet for this study

Summary

The purpose of this study is observe outcomes before and after a change in clinical practice in the threshold for management of severe hypertension in pregnancy and the post-partum period. Outcomes will be observed for 10 months under the current (traditional) clinical blood pressure threshold for acute treatment of hypertension, which is \>= 160 millimeters of mercury (mmHg) systolic blood pressure (SBP). This will be followed by one month of education about rationale for the new SBP threshold of \>= 180 mmHg and change of clinical guidelines. Then, there will be 10 months of observation after adopting the updated clinical threshold for acute antihypertensive treatment (\>= 180 SBP).

Conditions

  • Maternal Hypertension

Interventions

PROCEDURE

Clinical blood pressure threshold of SBP >= 160 mmHg for acute treatment of hypertension

Patients are treated for hypertension if SBP \>= 160 mmHg.

PROCEDURE

Clinical blood pressure threshold of SBP >= 180 mmHg for acute treatment of hypertension

Patients are treated for hypertension if SBP \>= 180 mmHg.

Sponsors & Collaborators

  • The University of Texas Health Science Center, Houston

    lead OTHER

Principal Investigators

  • Kristen Cagino, MD · The University of Texas Health Science Center, Houston

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-11
Primary Completion
2024-04-04
Completion
2024-04-04

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05881252 on ClinicalTrials.gov