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The Effect of Remimazolam on Opioid Induced Hyperalgesia

NCT05866315 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 108

Last updated 2023-10-06

No results posted yet for this study

Summary

The goal of this prospective, randomized, controlled study is to investigate the effect of remimazolam on opioid-induced hyperalgesia (OIH) in patients undergoing single port-laparoscopically assisted urologic surgery.

The main question\[s\] it aims to answer are:

* \[The mechanical hyperalgesia threshold\]
* \[Area of hyperalgesia around the surgical incision 24 h after surgery (cm\^2)\]

In three groups: Group RHR (Remimazolam- High-dose Remifentanil), Group DHR (Desflurane-low-dose Remifentanil) or Group DLR (Control).

Conditions

  • Hyperalgesia, Mechanical

Interventions

DRUG

Remimazolam

Administer remimazolam

DRUG

Desflurane

administer desflurane

DRUG

Remifentanil

administer remifentanil

Sponsors & Collaborators

  • Wonkwang University Hospital

    lead OTHER

Principal Investigators

  • Cheol Lee, M.D.,Ph.D. · Wonkwang University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-19
Primary Completion
2023-09-06
Completion
2023-09-15

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05866315 on ClinicalTrials.gov