Validation of HRM Score for the GERD Diagnosis

Summary

The goal of this prospective study is to validate a high resolution manometry score to predict pathologic GERD in patients with reflux symptoms. The main question it aims to answer is:

Is it possible to predict GERD on high resolution manometry? Participants will be asked to undergo high resolution manometry and pH-study

Conditions

• Gastro Esophageal Reflux

Interventions

DIAGNOSTIC_TEST

High resolution manometry

Standard chicago classification 4.0 HRM protocol

Sponsors & Collaborators

• University of Milan

  collaborator OTHER

• Medical University of Vienna

  collaborator OTHER

• Washington University School of Medicine

  collaborator OTHER

• University of Pisa

  collaborator OTHER

• Swedish Medical Center

  collaborator OTHER

• Hospital Universiti Sains Malaysia

  collaborator OTHER

• University of Campania Luigi Vanvitelli

  collaborator OTHER

• Universita degli Studi di Genova

  collaborator OTHER

• Jikei University School of Medicine

  collaborator OTHER

• Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

  collaborator OTHER

• University of Athens

  collaborator OTHER

• IRCCS Policlinico S. Donato

  lead OTHER

Principal Investigators

• Stefano Siboni, MD · IRCCS Policlinico S. Donato

Study Design

Allocation

NA

Purpose

DIAGNOSTIC

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-12-01

Primary Completion

2023-02-28

Completion

2023-04-29

Countries

• Italy

Study Locations