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Vitamin c Supplementation in the Prevention of CRPS Following Distal Radius Fractures

NCT05842395 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 220

Last updated 2026-03-19

No results posted yet for this study

Summary

Complex Regional Pain Syndrome type 1 is a pain syndrome that develops after a trauma, surgery, or idiopathically. The incidence after distal radius varies significantly in the literature. There are known contributing factors, such as the female sex but no effective treatment or prophylactic method. This study aims to investigate vitamin C's efficacy in preventing CRPS type 1 following distal radius fractures, as the literature states that it might play a role in prophylaxis.

Conditions

  • Distal Radius Fracture
  • Vitamine c
  • Prophylaxis

Interventions

DRUG

Vitamin C

Participants with distal radius fractures will take vitamin C supplementation with a daily dose of 1g orally for three months.

DRUG

Placebo

Participants with distal radius fractures will take daily Placebo orally for three months.

Sponsors & Collaborators

  • Damascus University

    lead OTHER

Principal Investigators

  • jaber ibrahim, MD PHD · Damascus university - faculty of medicine - department of surgery

  • hakam alasaad, MD · Damascus university - faculty of medicine - department of surgery

  • doried Diri, MD · Damascus university - faculty of medicine - department of surgery

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-15
Primary Completion
2024-05-30
Completion
2025-03-15

Countries

  • Syria

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05842395 on ClinicalTrials.gov