Patient Characteristics and Treatment Patterns From Early Crizanlizumab Use in Real-world Setting: Preliminary Analysis From Select Sickle Cell Centers
NCT05833022 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 297
Last updated 2023-04-27
Summary
This was a retrospective cohort study using secondary data from member sites of the National Alliance of Sickle Cell Centers (NASCC) with at least five patients who initiated crizanlizumab. Patients who were prescribed crizanlizumab were included in the cohort.
Conditions
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Pharmaceuticals · Novartis Pharmaceuticals
Eligibility
- Min Age
- 16 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-07-30
- Primary Completion
- 2022-04-18
- Completion
- 2022-04-18
Countries
- United States
Study Locations
More Related Trials
-
The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease
NCT06975865 ·Status: RECRUITING ·Phase: PHASE3
-
Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study
NCT04657822 ·Status: RECRUITING ·Phase: PHASE4
-
A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease
NCT03132324 ·Status: TERMINATED ·Phase: PHASE1
-
Clinical Study of BRL-101 in the Treatment of Sickle Cell Disease
NCT06287099 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Clinical Study of BRL-101 in Severe SCD
NCT06300723 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
A Study of IMR-687 in Subjects With Sickle Cell Disease
NCT04474314 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of IMR-687 in Adult Participants With Sickle Cell Anemia (Homozygous HbSS or Sickle-β0 Thalassemia)
NCT03401112 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients
NCT03814746 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease
NCT05012631 ·Status: RECRUITING ·Phase: PHASE2
-
An Extension Study of IMR-687 in Adult Patients With Sickle Cell Anemia
NCT04053803 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Genetics and Pain Severity in Sickle Cell Disease
NCT01441141 ·Status: COMPLETED
-
Diabetic Retinopathy and Sickle Trait
NCT00720317 ·Status: COMPLETED
-
Iron Mediated Vascular Disease in Sickle Cell Anemia Patients
NCT01239901 ·Status: COMPLETED
-
Risk-based Therapy for Sickle Cell Anemia: A Feasibility Study
NCT02090296 ·Status: WITHDRAWN ·Phase: PHASE2
-
Retrospective Real World Oxbryta® Data Collection and Analysis Study
NCT04930328 ·Status: COMPLETED
-
Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease
NCT02433158 ·Status: TERMINATED ·Phase: PHASE3
-
Safety and Efficacy of Orally Administered NUV001 Nutraceutical Supplement in Sickle Cell Disease Patients
NCT05791591 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Sickle Cell Disease: A Retrospective Chart Review
NCT01441375 ·Status: COMPLETED
-
Clinical Study on the Safety and Efficacy of BRL-101 in the Treatment of Sickle Cell Disease
NCT06287086 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
GBT021601-022: A Study of GBT021601 in Participants With Sickle Cell Disease (SCD)
NCT05632354 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Prasugrel Versus Placebo in Adult Sickle Cell Disease
NCT01167023 ·Status: COMPLETED ·Phase: PHASE2
-
Characteristics and Treatment Patterns of Patients With Sickle Cell Disease in Globin Research Network for Data and Discovery Registry
NCT06662812 ·Status: COMPLETED
-
Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease
NCT01123369 ·Status: COMPLETED
-
A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
NCT06546670 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Motivations, Expectations, and Decision-making of Sickle Cell Patients in Clinical Research
NCT03709303 ·Status: COMPLETED