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Investigation of Mohs Surgical Margins Using Two Photon Microscopy

NCT05814900 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 135

Last updated 2026-04-02

Study results available
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Summary

The goal of this clinical trial is to compare the use of two photon fluorescence microscopy for detecting residual basal cell carcinoma during Mohs surgery. The main question it aims to answer is:

• How similar are diagnosis of surgical margins to on two photon fluorescence microscopy compared to frozen section histology

Conditions

Interventions

DEVICE

Two photon microscopy imaging

Excised tissues will be imaged with two photon microscopy

Sponsors & Collaborators

  • Rochester Dermatologic Surgery

    collaborator OTHER

  • University of Rochester

    lead OTHER

Principal Investigators

  • Michael G Giacomelli, Ph.D · University of Rochester

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-06-20
Primary Completion
2025-06-19
Completion
2025-06-19
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05814900 on ClinicalTrials.gov