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Routine Versus As-Needed Stress Testing in Asymptomatic Patients With High-Risk Coronary Calcium

NCT05796739 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 3000

Last updated 2025-01-14

No results posted yet for this study

Summary

The purpose of the SMART-EXAM (SMart Angioplasty Research Team-Pragmatic Randomized Trial for Comparing Routine versus As-Needed EXercise or Pharmacologic Stress Testing in Asymptomatic Patients with High-Risk Coronary CalciuM) trial is to compare the major adverse cardiovascular events between routine stress testing and as-needed stress testing in asymptomatic patients with high-risk coronary calcium (Agatston Score ≥ 400) without proven ASCVD.

Conditions

  • Coronary Atherosclerosis Due to Calcified Coronary Lesion

Interventions

DIAGNOSTIC_TEST

Non-invasive stress test

Nuclear imaging, stress echocardiography, exercise electrocardiography, stress cardiac magnetic resonance imaging

DIAGNOSTIC_TEST

Medical treatment without further testing

Optimal medical treatment for primary prevention.

Sponsors & Collaborators

  • Samsung Medical Center

    lead OTHER

Principal Investigators

  • Seung-Hyuk Choi, MD · Samsung Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-07-03
Primary Completion
2029-06-30
Completion
2029-12-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05796739 on ClinicalTrials.gov