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Comparison of the Effectiveness of Two Glucocorticoid Regimens for Treatment of Graves' Orbitopathy

NCT05793359 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 62

Last updated 2023-03-31

No results posted yet for this study

Summary

The goal of this interventional study is to compare the effectiveness of two different glucocorticoid regimens for treatment of active moderate-to-severe Graves' orbitopathy. The main questions it aims to answer are:

1. Are the two glucocorticoid regimens similarly effective?
2. Do the two glucocorticoid regimens have similar safety profile? The patients involved are treated with one of the two glucocorticoid regimens. Their ocular status, therapeutic response and quality of life reassessed during the treatment, at its end, and 3 month later.

Conditions

  • Graves Ophthalmopathy

Interventions

DRUG

Methylprednisolone

methylprednisolone applied as intravenous infusions or intramuscularly

Sponsors & Collaborators

  • Medical University of Sofia

    lead OTHER

Principal Investigators

  • Mariya D Stoynova, PhD · Medical University of Sofia: Medicinski universitet-Sofia

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-07-25
Primary Completion
2021-02-25
Completion
2021-02-25

Countries

  • Bulgaria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05793359 on ClinicalTrials.gov