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Child Health, Nutrition and Microbiome Development

NCT05793294 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2026-01-05

No results posted yet for this study

Summary

Childhood malnutrition is a global public health issue with devastating consequences on the health, well-being, and psychosocial development of children. Emerging evidence suggests that malnourished children have immature gut microbiota compared to age-matched healthy controls and it does not repair even after nutritional interventions. The present study aims to characterize how the gut microbiome develops during the first two years of life in children residing in malnutrition endemic areas of Khyber Pakhtunkhwa, the region with the highest prevalence of childhood malnutrition in Pakistan and the region.

Conditions

  • Malnutrition
  • Stunting
  • Wasting
  • Underweight
  • Overweight and Obesity

Sponsors & Collaborators

  • University of Reading

    collaborator OTHER

  • Abdul Wali Khan University Mardan

    collaborator OTHER

  • University of Bern

    collaborator OTHER

  • National Institute of Health, Pakistan

    collaborator UNKNOWN

  • Khyber Medical University Peshawar

    lead OTHER

Principal Investigators

  • Muhammad Shahzad, PhD · Khyber Medical University

  • Zia Ul Haq, PhD · Khyber Medical University

Eligibility

Min Age
1 Day
Max Age
28 Days
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-05-10
Primary Completion
2025-05-30
Completion
2026-05-31

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05793294 on ClinicalTrials.gov