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Functional Disorders Moya Moya Young Patients

NCT05772572 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 21

Last updated 2025-09-12

No results posted yet for this study

Summary

Moya Moya disease is a rare condition of the vessels that supply blood to the brain. It normally occurs without apparent cause. In both children and adults, the disease is mainly manifested by strokes. Diagnosis is made on MRI and cerebral angiography. There is no treatment that can prevent the arteries in the brain from narrowing.

Surgical treatment may be a priority, especially in the early forms of the disease. Functional, painful disorders, in particular headaches, may persist after neurosurgical intervention, without any clear predictive factor being found. Otherwise there is a disjunction between the objectification of sequelae on MRI and painful complaints, sometimes a dissociation between the improvement of the objective parameters of perfusion and imaging, and functional somatic complaints.

The study focuses on improving knowledge of post-operative functional disorders in Moya Moya disease in children and adolescents, in order to propose interventions based on this knowledge and making it possible to reduce both functional complaints and depression, the anxiety which accompanies them, to decrease the impact on the quality of life and parental wandering in the installation of adapted accompaniments. For this, a half-day consultation will be intended in order to carry out questionnaires and standardized tests, the results of which will be reported and compared to known rates in the general population and the population of children with chronic diseases.

Conditions

  • Moyamoya Disease

Interventions

OTHER

Questionnaires

Questionnaires are completed only once and assess: * recorded questions about the disease and the operation for the parents and the patient, human figure drawing test and drawing of the operation for the patient * psychiatric questionnaires for parents and patients on anxiety and depression * behavior questionnaires for the parents and the patient: assessment of attachment * questionnaires for the parents and the patient concerning the family context, the quality of life

Sponsors & Collaborators

  • URC-CIC Paris Descartes Necker Cochin

    collaborator OTHER

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Lisa Ouss, MD · Assistance Publique - Hôpitaux de Paris

  • Manoelle Kossorotoff, MD · Assistance Publique - Hôpitaux de Paris

Eligibility

Min Age
7 Years
Max Age
25 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-02
Primary Completion
2024-02-09
Completion
2024-02-09

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05772572 on ClinicalTrials.gov