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Stimulation-evoked Calcitonin Gene-Related Peptide (CGRP) as Biomarker of Migraine

NCT05768828 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2023-03-14

No results posted yet for this study

Summary

This study aims to improve the management migraine by providing a more profound understanding of the interactions of pain disinhibition on the brain stem level and calcitonin gene-related peptide as a main mediator in the generation of migraine headaches. For this purpose, this observational study investigates established neurophysiological and blood biomarkers parameters in association with the clinical phenotype.

Conditions

Interventions

DIAGNOSTIC_TEST

Nociceptive Blink Reflex

Noxious trigeminal electrical stimulation at different interstimulus intervals using 1.5x the pain threshold in order to provoke a release of trigeminal CGRP

Sponsors & Collaborators

  • University Medicine Greifswald

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-02-20
Primary Completion
2023-05-30
Completion
2023-07-30

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05768828 on ClinicalTrials.gov