MedTrace Logo

Small Intestinal Bacterial Overgrowth in Critically Ill Patients

NCT05765994 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 52

Last updated 2023-03-13

No results posted yet for this study

Summary

Small intestinal bacterial overgrowth (SIBO) syndrome, though associated with potentially serious complications, has not been adequately studied to date in critically ill patients hospitalized in intensive care units (ICU).

A modified method for SIBO diagnosis is employed concerning a standard breath test. Specifically, as all participants are intubated and in need of mechanical ventilation, SIBO diagnosis is based on a non-invasive modified technique for sampling exhaled air from the ventilator tubes and performing a standard hydrogen breath test.

The primary objective of this study is assessment of the prevalence of SIBO on ICU patients. Secondary outcomes include investigation of the effects of SIBO on ventilator associated pneumonia, as well as ICU length of stay and all-cause in-hospital mortality rate in critically ill patients.

Conditions

  • Small Intestinal Bacterial Overgrowth
  • Critical Illness
  • Intensive Care Unit

Interventions

DIAGNOSTIC_TEST

Modified hydrogen breath test

A modified technique to obtain expired hydrogen from the ventilator tubes is performed. A connection with a valve attached to a collecting bag is inserted at the end of the expiratory limb of the breathing circuit for exhaled air collection.

Sponsors & Collaborators

  • University of Ioannina

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-11-19
Primary Completion
2019-07-08
Completion
2019-07-08

Countries

  • Greece

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05765994 on ClinicalTrials.gov