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Bimanual Motor Skill Learning in Acute Stroke

NCT05760846 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 160

Last updated 2024-12-16

No results posted yet for this study

Summary

The subacute phase of stroke provides a window into how a lesion perturbs sensorimotor functions prior to reorganisation driven by plasticity and neurorehabilitation. The recovery from motor impairment has been extensively studied, but it is currently unknown whether motor skill learning (MSkL) is enhanced or impaired during acute stroke, especially bimanual motor skill learning (bim-MSkL), which likely requires more motor-attentional-cognitive resources than unimanual MSkL.

The goals of this project are: to determine the neural substrates critical to achieve proximal and distal bimanual motor skill learning (bim-MSkL) by specifying whether (sub)acute stroke to different brain areas (cortical and subcortical) induce specific deficits in bimanual and/or distal bim-MSkL, which behavioral components are involved in bim-MSkL, and whether damage to the motor, sensory and inter-hemispheric pathways specifically impairs proximal and/or distal bim-MSkL.

Conditions

  • Stroke, Acute
  • Stroke, Subacute

Interventions

DEVICE

REAplan®

motor skill learning with the REAplan® rehabilitation robot, to be performed with both arms

DEVICE

Dextrain Manipulandum®

motor skill learning with the Dextrain Manipulandum® dexterity tool to be performed with both hands

Sponsors & Collaborators

  • University Hospital of Mont-Godinne

    lead OTHER

Principal Investigators

  • Yves Vandermeeren, MD, PhD · UCLouvain IONS

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-17
Primary Completion
2028-03-31
Completion
2028-10-31

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05760846 on ClinicalTrials.gov