Zimberelimab Plus Metformin for Recurrent Ovarian Clear Cell Carcinoma
NCT05759312 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2023-03-08
Summary
This study aims to evaluate the safety and effectiveness of zimberelimab combined with metformin in treating relapsed/persistent ovarian clear cell carcinoma.
Conditions
Interventions
- DRUG
-
Zimberelimab
Zimberelimab 240mg IV every 2 weeks
- DRUG
-
Metformin Hydrochloride
Metformin 2000mg PO QD
Sponsors & Collaborators
-
Fudan University
lead OTHER
Principal Investigators
-
Libing Xiang · Department of Gynecologic Oncology, Zhongshan Hospital, Fudan University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-03-31
- Primary Completion
- 2025-02-28
- Completion
- 2025-02-28
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