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Effects of Low LH Serum Levels on Ovarian Pick-up Outcome

NCT05755529 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 43

Last updated 2023-03-06

No results posted yet for this study

Summary

Luteinizing hormone (LH) plays a key role for normal follicular development and oocyte maturation in controlled ovarian stimulation. In particular, LH stimulates the proliferation and differentiation of theca cells for the secretion of androgens, which synergistically increase the production of estrogen. This study aimed to investigate the effects of low LH concentrations on oocyte retrieval, fertilization and embryo development in patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). Patients undergoing IVF/ICSI were prospectively analyzed, subdividing them into three groups according to their age. Serum LH levels were evaluated at day 3, during stimulation (day 10) and before ovulation induction (day 12).

Conditions

  • Infertility, Female
  • ART

Sponsors & Collaborators

  • University of Palermo

    lead OTHER

Principal Investigators

  • Jessica Dragotto, Biologist · Clinica del Mediterraneo - Ragusa

  • Giovanni Bracchitta, M.D. · Clinica del Mediterraneo - Ragusa

  • Antonio Simone Laganà, M.D., Ph.D. · University of Palermo

  • Andrea Etrusco, M.D. · University of Palermo

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-31
Primary Completion
2023-03-31
Completion
2023-03-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05755529 on ClinicalTrials.gov