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Transbronchial Lung Cryobiopsy in Undiagnosed Acute Respiratory Failure

NCT05754866 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2024-02-07

No results posted yet for this study

Summary

In patients with acute hypoxemic respiratory failure whose diagnosis is not established after initial evaluation, obtaining a histopathological diagnosis may improve the patients' prognosis. In our previous retrospective-controlled study, transbronchial lung cryobiopsy (TBLC) can lead to an increased chance of establishing a diagnosis compared with transbronchial lung biopsy (TBLB), with an acceptable safety profile. Therefore, further prospective randomized controlled studies exploring whether TBLC leads to improved prognosis for such patients are warranted.

Conditions

  • Acute Respiratory Failure
  • Acute Respiratory Distress Syndrome

Interventions

PROCEDURE

Transbronchial lung cryobiopsy

Lung tissue was obtained by transbronchial lung cryobiopsy for subsequent pathology and clinical diagnosis.

PROCEDURE

Transbronchial lung biopsy

Lung tissue was obtained by transbronchial lung biopsy for subsequent pathology and clinical diagnosis.

Sponsors & Collaborators

  • China-Japan Friendship Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-01
Primary Completion
2025-11-01
Completion
2025-11-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05754866 on ClinicalTrials.gov