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NLRP3 Inflammasome Activation Among Patients During Acute Gout Flares

NCT05744297 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2023-05-12

No results posted yet for this study

Summary

Gout is a chronic joint disease associated with deposition of monosodium urate crystals, as a consequence of hyperuricemia. Gout is an intermittent flaring condition and acute gout flares are driven by NLRP3 inflammasome and IL1-beta production.

However pathogenesis of acute gout flares remains poorly known in vivo in human.

The aim of this study is to evaluate NLRP3 inflammasome activation in vivo in patients cells during acute gout flares.

Conditions

  • Gout Arthritis

Sponsors & Collaborators

  • Centre Hospitalier Saint Joseph Saint Luc de Lyon

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-28
Primary Completion
2023-06-30
Completion
2023-10-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05744297 on ClinicalTrials.gov