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Changes of Visual Field Defects After IAT for CRAO

NCT05739487 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 27

Last updated 2023-02-22

No results posted yet for this study

Summary

Central retinal artery occlusion (CRAO) is an ophthalmic emergency which leads to devastating visual function defects and poor prognosis. Though traditional conservative treatments are widely used, none of them is proved to be effective. A number of meta-analyses and observational studies indicate intravenous thrombolysis to be beneficial in CRAO. Selective intra-arterial thrombolysis (IAT) introducing rt-PA directly into the ophthalmic circulation by super-selective microcatheterization may reduce the complications such as intracranial and systemic hemorrhage. The residual visual field is significant for patients with CRAO who have poor central visual acuity. Thus, it is clinically significant to study the changes in visual fields in eyes with CRAO.

Conditions

  • Central Retinal Artery Occlusion
  • Visual Field
  • Intra-arterial Thrombolysis

Interventions

PROCEDURE

selective intra-arterial thrombolysis

IAT introduces rt-PA (50mg) directly into the ophthalmic circulation by super-selective microcatheterization

Sponsors & Collaborators

  • Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

    lead OTHER

Principal Investigators

  • Ping Fei, MD#PhD · Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-07-01
Primary Completion
2022-03-31
Completion
2022-03-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05739487 on ClinicalTrials.gov